Universitätsmedizin Greifswald
2 ARTICLES PUBLISHED IN JoVE
Immunology and Infection
Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
Tobias Traeger *1, Pia Koerner *1, Wolfram Kessler 1, Katharina Cziupka 1, Stephan Diedrich 1, Alexandra Busemann 1, Claus-Dieter Heidecke 1, Stefan Maier 1
1Department of Surgery, University of Greifswald
The Colon Ascendens Stent Peritonitis (CASP) is a highly standardized model for polymicrobial abdominal sepsis in rodents. This article describes the surgical procedure of CASP. The CASP model and its variants allow the systematic investigation of various problems concerning the subject of sepsis.
Medicine
Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
Annabel Kleinwort 1, Paula Döring 2, Christine Hackbarth 1, Maciej Patrzyk 1, Claus-Dieter Heidecke 1, Tobias Schulze 1
1Department of General Surgery, Visceral, Thoracic and Vascular Surgery, Universitätsmedizin Greifswald, 2Institute of Pathology, Universitätsmedizin Greifswald
Murine distal colostomy provides a murine model for human diversion colitis, a predominantly lymphocytic colitis in colon segment excluded from the fecal stream.
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