Australian Research Council Centre of Excellence for Integrative Brain Function

1 ARTICLES PUBLISHED IN JoVE

Behavior

Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET

Sharna D. Jamadar^1,2,3, Phillip G.D. Ward^1,2,3, Alexandra Carey^1,4, Richard McIntyre^1,4, Linden Parkes^1,3, Disha Sasan¹, John Fallon¹, Edwina Orchard^1,2,3, Shenpeng Li^1,5, Zhaolin Chen^1,5, Gary F Egan^1,2,3

¹Monash Biomedical Imaging, Monash University, ²Australian Research Council Centre of Excellence for Integrative Brain Function, ³Turner Institute for Brain and Mental Health, Monash University, ⁴Department of Medical Imaging, Monash Health, ⁵Department of Electrical and Computer Systems Engineering, Monash University

This manuscript describes two radiotracer administration protocols for FDG-PET (constant infusion and bolus plus infusion) and compares them to bolus administration. Temporal resolutions of 16 s are achievable using these protocols.