An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity TestingHedwig M. Braakhuis 1, Ruiwen He 1,2, Rob J. Vandebriel 1, Eric R. Gremmer 1, Edwin Zwart 1, Jolanda P. Vermeulen 1, Paul Fokkens 1, John Boere 1, Ilse Gosens 1, Flemming R. Cassee 1,2
1National Institute for Public Health and the Environment (RIVM), 2Institute for Risk Assessment Sciences (IRAS)
Described is the cell culture and exposure method of an in vitro bronchial model for realistic, repeated inhalation exposure to particles for toxicity testing.
