All India Institute of Medical Sciences (AIIMS)

1 ARTICLES PUBLISHED IN JoVE

Medicine

Protocol for Developing a Femur Osteotomy Model in Wistar Albino Rats

Aayush Aryal¹, Pawan Kumar Pagaku², Devanjan Dey², Sagar Tyagi², Vadanya Shrivastava², Aditi Bhattacharya², Sweety Rani², Debdatta Nayak⁶, Anil Khurana⁶, Puneet Khanna³, Ankur Goyal⁴, Asit Ranjan Mridha⁵, Bhavuk Garg¹, Sudip Sen²

¹Department of Orthopedics, All India Institute of Medical Sciences (AIIMS), ²Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), ³Department of Anaesthesiology Pain Medicine and Critical Care, All India Institute of Medical Sciences (AIIMS), ⁴Department of Radiodiagnosis, All India Institute of Medical Sciences (AIIMS), ⁵Department of Pathology, All India Institute of Medical Sciences (AIIMS), ⁶Central Council for Research in Homoeopathy (CCRH)

Here, we present a protocol to iatrogenically fracture the shaft of the femur of Wistar albino rats and follow up on the development of the callus. This femur osteotomy model can help researchers evaluate the process of fracture healing and to study how a drug could influence fracture healing.