Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine
2 ARTICLES PUBLISHED IN JoVE
Medicine
Network Pharmacology Prediction and Experimental Validation of Trichosanthes-Fritillaria thunbergii Action Mechanism Against Lung Adenocarcinoma
Xu-yi Zhao 1, Yun-yue Yang 1, Jing-li Feng 1, Cui-ling Feng 2
1Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine, 2Traditional Chinese Medicine Department, Peking University People's Hospital
This study reveals the mechanism of Trichosanthes-Fritillaria thunbergii in treating lung adenocarcinoma based on network pharmacology and experimental verification. The study also demonstrates that the PI3K/AKT signaling pathway plays a vital role in the action of Trichosanthes-Fritillaria thunbergii in treating lung adenocarcinoma.
Medicine
Antagonistic Effect of Jiawei Shengjiang San on a Rat Model of Diabetic Nephropathy: Related to EGFR/MAPK3/1 Signaling Pathway
Jingyu Mao *1, Qin Lu *2, Fei Gao 3, Hao Liu 4, Jinchuan Tan 5
1Graduate School, Hebei University of Chinese Medicine, 2School of Basic Medical Sciences, Hebei University of Chinese Medicine, 3Department of Endocrinology and Nephrology, Renal Research Institute of Beijing University of Chinese Medicine, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, 4Hebei Province Academy of Chinese Medicine Sciences, 5Department of Nephrology, First Affiliated Hospital, Hebei University of Chinese Medicine
Here, we present a protocol describing network pharmacology and molecular docking techniques to explore the mechanism of action of Jiawei Shengjiang San (JWSJS) in treating diabetic nephropathy.
