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Chapter 12

Mendelian Genetics

Punnett 方块
Punnett 方块
Overview A Punnett square displays the possible genotypes offspring can inherit from two parental genotypes. If a trait’s inheritance pattern ...
单杂交杂交
单杂交杂交
Overview In the 1850s and 1860s, Gregor Mendel investigated inheritance by performing monohybrid crosses in pea plants. He crossed two plants that were ...
双杂交杂交
双杂交杂交
Overview To determine whether traits are inherited together or separately, Gregor Mendel crossed pea plants that differed in two traits. These parental ...
三杂交杂交
三杂交杂交
Trihybrid Crosses Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A ...
独立分类法则
独立分类法则
While Mendel’s Law of Segregation states that the two alleles for one gene are separated into different gametes, a different question of how ...
卡方分析
卡方分析
The chi-square test is a statistical hypothesis test. It is used to check whether there is a significant difference between an expected value and an ...
系谱分析
系谱分析
Overview A pedigree is a diagram displaying a family’s history of a trait. Analyzing pedigrees can reveal (1) whether a trait is dominant or ...
多个等位基因性状
多个等位基因性状
The Concept of Multiple Allelism Multiple allelism describes genes that exist in three or more allelic forms. Although diploid organisms, like humans, ...
不完全支配
不完全支配
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid ...
致命等位基因
致命等位基因
Agouti: A Lethal Allele Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is ...
多基因性状
多基因性状
When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered ...
背景和环境影响表型
背景和环境影响表型
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as ...
X 和 Y 染色体
X 和 Y 染色体
Among mammals, the gender of an organism is determined by the sex chromosomes. Humans have two sex chromosomes, X and Y. Every human diploid cell has 22 ...
Y 染色体决定男性
Y 染色体决定男性
The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human ...
X 染色体与常染色体的比率
X 染色体与常染色体的比率
In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined ...
X 链接特征
X 链接特征
In most mammalian species, females have two X sex chromosomes and males have an X and Y. As a result, mutations on the X chromosome in females may be ...
性相关疾病
性相关疾病
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological ...
剂量补偿
剂量补偿
In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one ...
X 灭活
X 灭活
The human X chromosome contains over ten times the number of genes as in the Y chromosome. Since males have only one X chromosome, and females have two, ...
血型
血型
Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper ...
输血和凝集
输血和凝集
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood ...
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