Chapter 9
Cardiovascular Drugs: Antihypertensive Drugs
心血管药物:根据治疗适应症进行分类
Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These ...
高血压和血压调节
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage ...
抗高血压药物:利尿剂的作用
Diuretics are antihypertensive drugs used to treat hypertension resulting from sodium and water retention. Sodium, vital for fluid balance and nerve or ...
抗高血压药物:噻嗪类利尿剂
Thiazide diuretics are sulfonamide derivatives featuring a benzothiadiazine ring system in their molecular structure. Based on this structure, thiazide ...
抗高血压药物:保钾利尿剂
Liddle syndrome is a genetically inherited form of hypertension characterized by the overactivity of epithelial sodium channels in the nephron, the ...
抗高血压药物:β1受体阻滞剂的作用
β1-receptors are primarily located in the heart and kidneys. In cardiac myocytes, these receptors interact with neurotransmitters released by the ...
抗高血压药物:非选择性β受体阻滞剂的作用
β receptors are classified into three subclasses: β1, β2, and β3. β1 receptors are primarily located in the heart and kidneys. ...
抗高血压药物:钙通道阻滞剂的作用
Calcium ions are essential to contract smooth muscle cells in blood vessels. They enter these cells through voltage-dependent calcium channels, ...
抗高血压药物:血管紧张素转换酶抑制剂
Angiotensin-converting enzyme (ACE), a vital component of the renin-angiotensin-aldosterone system, is abundant in lung endothelial cells. ACE converts ...
抗高血压药物:血管紧张素II受体阻滞剂
In the renin-angiotensin-aldosterone system, a hormone called angiotensin II plays a crucial role. It binds to the AT1 receptors in vascular smooth ...
抗高血压药物:直接肾素抑制剂
The renin-angiotensin-aldosterone system (RAAS) is an intricate physiological pathway involving numerous enzymes and hormones, including renin, ...
抗高血压药物:血管扩张剂
Vasodilators, primarily affecting the smooth muscles within arterial and venous walls, are commonly used for hypertension treatment. Medications such as ...
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