Functional Isolation of Subsarcolemmal and Intermyofibrillar Mitochondria from Skeletal Muscle
2:15
Mitochondrial Protein Import
6:33
Results: The Evaluation of Protein Import Capacity into Mitochondria
8:17
Conclusion
Transcript
Mitochondria rely heavily on the nuclear genome, despite having their own DNA. Thus, a highly-regulated mechanism of import is required. This method helps study the process and how it can adapt to external stimuli.
This is the only biochemic
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Mitochondria are key metabolic organelles that exhibit a high level of phenotypic plasticity in skeletal muscle. The import of proteins from the cytosol is a critical pathway for organelle biogenesis, essential for the expansion of the reticulum and the maintenance of mitochondrial function. Therefore, protein import serves as a barometer of cellular health.
