<meta charset="utf8"></head><body>穴位和耳石膏疗法治疗 AECOPD 患者睡眠障碍

<ol>
	<li>Luo, M. C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Radical+oxygen+species:+an+important+breakthrough+point+for+botanical+drugs+to+regulate+oxidative+stress+and+treat+the+disorder+of+glycolipid+metabolism.">Radical oxygen species: an important breakthrough point for botanical drugs to regulate oxidative stress and treat the disorder of glycolipid metabolism.</a> Front Pharmacol. 14, 1166178 (2023).</li><li>Zhu, L. Y., Lu, X. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Discussion+on+the+correlation+between+the+pathogenesis+of+lung+deficiency+and+collateral+stasis+and+oxidative+stress+in+COPD.">Discussion on the correlation between the pathogenesis of lung deficiency and collateral stasis and oxidative stress in COPD.</a> Journal of Liaoning University of Traditional Chinese Medicine. 3, (2024).</li><li>Ren, C. S., Wang, G. S., Qian, G. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Nosogenesis+of+chronic+obstructive+pulmonary+disease+and+the+perplexity+and+hope+of+treatment.">Nosogenesis of chronic obstructive pulmonary disease and the perplexity and hope of treatment.</a> Chinese Journal of Lung Diseases (Electronic Edition). 12 (2), 127-141 (2019).</li><li>Ren, C. X., Liu, H. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Progress+in+management+and+intervention+of+sleep+disorders+in+patients+with+chronic+obstructive+pulmonary+disease.">Progress in management and intervention of sleep disorders in patients with chronic obstructive pulmonary disease.</a> J Med Res. 50 (02), 153-156 (2021).</li><li>Tsai, S. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Chronic+obstructive+pulmonary+disease+and+sleep+related+disorders.">Chronic obstructive pulmonary disease and sleep related disorders.</a> Curr Opin Pulm Med. 23 (2), 124-128 (2017).</li><li>Latshang, T. D., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Sleep+and+breathing+disturbances+in+patients+with+chronic+obstructive+pulmonary+disease+traveling+to+altitude:+a+randomized+trial.">Sleep and breathing disturbances in patients with chronic obstructive pulmonary disease traveling to altitude: a randomized trial.</a> Sleep. 42 (1), (2019).</li><li>Chabowski, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Sleep+disorders+and+adherence+to+inhalation+therapy+in+patients+with+chronic+obstructive+pulmonary+disease.">Sleep disorders and adherence to inhalation therapy in patients with chronic obstructive pulmonary disease.</a> Adv Exp Med Biol. 1160, 43-52 (2019).</li><li>Du, D., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Prevalence+and+clinical+characteristics+of+sleep+disorders+in+chronic+obstructive+pulmonary+disease:+A+systematic+review+and+meta-analysis.">Prevalence and clinical characteristics of sleep disorders in chronic obstructive pulmonary disease: A systematic review and meta-analysis.</a> Sleep Med. 112, 282-290 (2023).</li><li>De Crescenzo, F., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Comparative+effects+of+pharmacological+interventions+for+the+acute+and+long-term+management+of+insomnia+disorder+in+adults:+a+systematic+review+and+network+meta-analysis.">Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis.</a> Lancet. 400 (10347), 170-184 (2022).</li><li>Lu, Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Comparative+effectiveness+of+multiple+acupuncture+therapies+for+primary+insomnia:+a+systematic+review+and+network+meta-analysis+of+randomized+trial.">Comparative effectiveness of multiple acupuncture therapies for primary insomnia: a systematic review and network meta-analysis of randomized trial.</a> Sleep Med. 93, 39-48 (2022).</li><li>. Global strategy for the prevention, diagnosis and management of OPD: 2024 report Available from: <a target="_blank" href="https://goldcopd.org/2024-gold-report/">https://goldcopd.org/2024-gold-report/</a> (2024)</li><li>. International classifcation of sleep disorders Available from: <a target="_blank" href="https://aasm.org/clinical-resources/international-classification-sleep-disorders/">https://aasm.org/clinical-resources/international-classification-sleep-disorders/</a> (2014)</li><li>American Psychiatric Association. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> Diagnostic and Statistical Manual of Mental Disorders. , (2022).</li><li>Tang, P. T., Yin, C. Y., Cai, L. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Clinical+study+on+auricular+point+pressing+for+acute+exacerbation+of+chronic+obstructive+pulmonary+disease+complicated+with+insomnia.">Clinical study on auricular point pressing for acute exacerbation of chronic obstructive pulmonary disease complicated with insomnia.</a> New Journal of Traditional Chinese Medicine. 55 (4), 182-185 (2023).</li><li>National Administration of Traditional Chinese Medicine. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> Nomenclature and location of meridian points. , (2021).</li><li>National Administration of Traditional Chinese Medicine. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> Nomenclature and Location of auricular points. , (2008).</li><li>Liu, C., Wei, X. C., Lu, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Mechanism+and+efficacy+of+acupoint+application+in+the+treatment+of+insomnia+in+recent+ten+years.">Mechanism and efficacy of acupoint application in the treatment of insomnia in recent ten years.</a> Smart Healthcare. 8 (5), 29-32 (2022).</li><li>Zhao, K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Acupuncture+for+the+treatment+of+insomnia.">Acupuncture for the treatment of insomnia.</a> Int Rev Neurobiol. 111, 217-234 (2013).</li><li>Liu, G. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> The effects of Chinese medicine patches with acupoint application on monamine neurotransmitter and IL-1&#946; in hypothalamus of Insomnia Rats [Master's Thesis]. , (2007).</li><li>Li, Q. S., Wang, S. X. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Protective+effects+of+eleutherosides+acupoint+application+on+rats+with+sleep+deprivation.">Protective effects of eleutherosides acupoint application on rats with sleep deprivation.</a> Mil Med of Joint Log. 16 (2), 11-14 (2002).</li><li>Hu, J. X., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Effects+of+Jingyi+Anshen+powder+acupoint+application+on+behavior+and+the+related+cytokines+in+rats+with+insomnia.">Effects of Jingyi Anshen powder acupoint application on behavior and the related cytokines in rats with insomnia.</a> Western Journal of Traditional Chinese Medicine. 31 (11), 41-45 (2021).</li><li>Chen, Y. Y., Chen, Y. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Forty-five+cases+of+elderly+patients+with+acute+exacerbation+of+chronic+obstructive+pulmonary+disease+treated+with+the+aid+of+acupoint+application+of+white+mustard+powder.">Forty-five cases of elderly patients with acute exacerbation of chronic obstructive pulmonary disease treated with the aid of acupoint application of white mustard powder.</a> Zhejiang Journal of Traditional Chinese Medicine. 56 (5), 357 (2021).</li><li>Shao, B., Shen, Z. L., Chen, J., Chen, L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Clinical+observation+on+55+cases+of+acute+phase+of+chronic+obstructive+pulmonary+disease+with+phlegm+and+turbid+lung+obstruction+treated+by+acupoint+patch+therapy.">Clinical observation on 55 cases of acute phase of chronic obstructive pulmonary disease with phlegm and turbid lung obstruction treated by acupoint patch therapy.</a> Hunan Journal of Traditional Chinese Medicine. 34 (7), 116-118 (2018).</li><li>Duan, W. B., Zhu, F. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Effects+of+acupoint+application+combined+with+traditional+Chinese+medical+care+on+pulmonary+function,+immune+function+and+vascular+endothelial+function+indexes+of+AECOPD+patients.">Effects of acupoint application combined with traditional Chinese medical care on pulmonary function, immune function and vascular endothelial function indexes of AECOPD patients.</a> Guangming Journal of Chinese Medicine. 37 (3), 513-515 (2022).</li><li>Yang, Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> Clinical observation of Huangqin Wendan decoction combined with ear acupoint pressing bean in treatment of AECOPD with insomnia due to phlegm heat accumulation [Master's Thesis]. , (2021).</li><li>Wang, X. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Application+effect+of+auricular+pressure+bean+care+combined+with+acupoint+patch+on+sputum+symptoms+in+patients+with+acute+exacerbation+of+chronic+obstructive+pulmonary+disease.">Application effect of auricular pressure bean care combined with acupoint patch on sputum symptoms in patients with acute exacerbation of chronic obstructive pulmonary disease.</a> Jilin Med. J. 43 (10), 2852-2854 (2022).</li><li>Dong, Z. Q. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Clinical+analysis+of+acupoint+patch+combined+with+auricular+pressure+bean+in+the+treatment+of+acute+exacerbation+of+COPD.">Clinical analysis of acupoint patch combined with auricular pressure bean in the treatment of acute exacerbation of COPD.</a> Shenzhen Journal of Integrative Traditional Chinese. 28 (10), 73-75 (2018).</li><li>Wang, Y. J., Ai, Q. X. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Effects+of+Chinese+medicine+characteristic+nursing+techniques+on+exercise+endurance+and+lung+function+in+patients+with+acute+exacerbation+of+chronic+obstructive+pulmonary+disease.">Effects of Chinese medicine characteristic nursing techniques on exercise endurance and lung function in patients with acute exacerbation of chronic obstructive pulmonary disease.</a> The Journal of Medical Theory and Practice. 35 (9), 1574-1576 (2021).</li><li>Wang, X. H., Xiao, L. Y., Wang, B. F., Yuan, Y. D., Pan, W. S., Shi, Y. Z. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Influence+of+auricular+plaster+therapy+on+sleeping+structure+in+OSAS+patients.">Influence of auricular plaster therapy on sleeping structure in OSAS patients.</a> J Tradit Chin Med. 29 (1), 3-5 (2009).</li><li>Lei, X. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Observation+on+the+effect+of+auricular+point+pressing+beans+in+the+treatment+of+insomnia.">Observation on the effect of auricular point pressing beans in the treatment of insomnia.</a> Journal of Frontiers of Medicine. 9 (13), 195-196 (2019).</li><li>Tian, T., Wang, D. W., Li, Y., Song, L. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Observation+on+the+effect+of+acupuncture+and+moxibustion+combined+with+auricular+point+pressing+pill+intervention+on+insomnia+patients+with+coronary+heart+disease.">Observation on the effect of acupuncture and moxibustion combined with auricular point pressing pill intervention on insomnia patients with coronary heart disease.</a> Journal of Practical Traditional Chinese Internal Medicine. 37 (11), 52-55 (2023).</li><li>Zhang, Q., Qiao, Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Research+Progress+on+antiasthmatic+effect+and+mechanism+of+Ding+chuan+and+Tian+tu+acupoints.">Research Progress on antiasthmatic effect and mechanism of Ding chuan and Tian tu acupoints.</a> Journal of Guangxi University of Chinese Medicine. 23 (03), 64-66 (2020).</li><li>Fu, K. L., Lin, K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Clinical+observation+on+point+application+treating+80+patients+of+chronic+obstructive+pulmonary+diseases.">Clinical observation on point application treating 80 patients of chronic obstructive pulmonary diseases.</a> Journal of Traditional Chinese Medicine. 56 (11), 948-952 (2015).</li><li>Wu, Z. L., Zhang, Q. R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Ancient+and+modern+research+on+Fei+shu+point.">Ancient and modern research on Fei shu point.</a> Liaoning Journal of Traditional Chinese Medicine. 34 (04), 504-505 (2007).</li><li>Gu, Z. L., Xie, Y., Wang, Y., Xu, B. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Literature+analysis+on+the+mechanism+of+acupuncture+in+the+treatment+of+chronic+obstructive+pulmonary+disease.">Literature analysis on the mechanism of acupuncture in the treatment of chronic obstructive pulmonary disease.</a> Journal of Traditional Chinese Medicine. 62 (22), 2003-2010 (2021).</li><li>Liu, X. L., Yi, K. L., Zhu, W. X., Mi, H., Yuan, Y. F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Research+on+Acupoint+selection+for+insomnia+treated+by+auricular+acupoint+pressing+beans+based+on+data+mining+technology.">Research on Acupoint selection for insomnia treated by auricular acupoint pressing beans based on data mining technology.</a> Prog Mod Biomed. 22 (21), 4168-4174 (2022).</li><li>Du, B. X., Zhao, X. D., Wen, D., Xue, X. S., Wang, W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Research+progress+of+auricular+point+sticking+in+the+treatment+of+depression+with+insomnia.">Research progress of auricular point sticking in the treatment of depression with insomnia.</a> World J of Sleep Med. 9 (11), 2231-2234 (2022).</li></ol>

<table><tbody><tr><td>75% alcohol cotton balls</td><td>Shanghai Honglong Industrial Co., Ltd</td><td>20231116</td><td></td></tr><tr><td>Acupoint patches</td><td>Jiangsu Guangyi Medical Dressing Co., Ltd</td><td>20230718</td><td></td></tr><tr><td>Chinese herbal medicine</td><td>Guangdong Kanghe Pharmaceutical Co.,Ltd</td><td>230802</td><td></td></tr><tr><td>Magnetic treatment plaster</td><td>Suzhou Medical Supplies Factory Co., Ltd</td><td>233010</td><td></td></tr><tr><td>Medical disposable sterilization rubber gloves</td><td>Shandong Yuyuan Latex Gloves Co., Ltd</td><td>230806R22</td><td></td></tr><tr><td>Medical hand disinfectants</td><td>Shanghai Likang Disinfection High tech Co., Ltd</td><td>20230113J</td><td></td></tr><tr><td>Medical tape</td><td>Minnesota Mining Manufacturing Medical Equipment (Shanghai) Co., Ltd</td><td>23063GO</td><td></td></tr><tr><td>Sterile cotton swabs</td><td>Shanghai Honglong Medical Equipment Co., Ltd</td><td>20231108</td><td></td></tr><tr><td>Tweezers</td><td>Yangzhou Huayue Technology Development Co., Ltd</td><td>20231106</td><td></td></tr></tbody></table>

acupoint application combined with ear plaster therapy for treating sleep disorders with acute exacerbation of chronic obstructive pulmonary disease

<meta charset="utf8"></head><body>作者聚焦：治疗急性慢性阻塞性肺病睡眠障碍的中医 — 一种安全、经济高效的方法

穴位应用联合耳石膏治疗慢性阻塞性肺疾病急性加重的睡眠障碍

Chronic Obstructive Pulmonary Disease (COPD) is a lung disease characterized by persistent airflow limitation, which is not fully reversible and ...

acupoint-application-combined-with-ear-plaster-therapy-for-treating

Research

JoVE Journal

Medicine

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

685 次观看.  Hospital of Chengdu University of Traditional Chinese Medicine. 我们的研究重点是通过穴位应用和耳石膏疗法治疗 COPD 急性加重患者的睡眠障碍。我们的目标是进一步研究，通过中医技术可以有效改善患者的症状或体征。我们的方案还需要添加关于穴位应用联合耳石膏治疗是否可以改善急性慢性阻塞性肺症状的临床数据以及合并的数据。我们的结果提供了一种有效、安全和简单的治疗方法，与现代医学药物...

视频: 作者聚焦：治疗急性慢性阻塞性肺病睡眠障碍的中医 — 一种安全、经济高效的方法

Evaluation of Respiratory Muscle Activation Using Respiratory Motor Control Assessment (RMCA) in Individuals with Chronic Spinal Cord Injury

During breathing, activation of respiratory muscles is coordinated by integrated input from the brain, brainstem, and spinal cord. When this coordination is disrupted by spinal cord injury (SCI), control of respiratory muscles innervated below the injury level is compromised1,2 leading to respiratory muscle dysfunction and pulmonary complications. These conditions are among the leading causes of death in patients with SCI3. Standard pulmonary function tests that assess respiratory motor function include spirometrical and maximum airway pressure outcomes: Forced Vital Capacity (FVC), Forced Expiratory Volume in one second (FEV1), Maximal Inspiratory Pressure (PImax) and Maximal Expiratory Pressure (PEmax)4,5. These values provide indirect measurements of respiratory muscle performance6. In clinical practice and research, a surface electromyography (sEMG) recorded from respiratory muscles can be used to assess respiratory motor function and help to diagnose neuromuscular pathology. However, variability in the sEMG amplitude inhibits efforts to develop objective and direct measures of respiratory motor function6. Based on a multi-muscle sEMG approach to characterize motor control of limb muscles7, known as the voluntary response index (VRI)8, we developed an analytical tool to characterize respiratory motor control directly from sEMG data recorded from multiple respiratory muscles during the voluntary respiratory tasks. We have termed this the Respiratory Motor Control Assessment (RMCA)9. This vector analysis method quantifies the amount and distribution of activity across muscles and presents it in the form of an index that relates the degree to which sEMG output within a test-subject resembles that from a group of healthy (non-injured) controls. The resulting index value has been shown to have high face validity, sensitivity and specificity9-11. We showed previously9 that the RMCA outcomes significantly correlate with levels of SCI and pulmonary function measures. We are presenting here the method to quantitatively compare post-spinal cord injury respiratory multi-muscle activation patterns to those of healthy individuals.

Evaluation of Respiratory Muscle Activation Using Respiratory Motor Control Assessment RMCA in Individuals with Chronic Spinal Cord Injury

The purpose of this publication is to present our original work on a multi-muscle surface electromyographic approach to quantitatively characterize respiratory muscle activation patterns in individuals with chronic spinal cord injury using vector-based analysis.

评价呼吸肌慢性脊髓损伤个人使用呼吸电机控制评估（RMCA）

During breathing, activation of respiratory muscles is coordinated by integrated input from the brain, brainstem, and spinal cord. When this coordination ...

科研

医学

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation and lung parenchymal destruction. It has a very high incidence in aging populations. The current conventional therapies for COPD focus mainly on symptom-modifying drugs; thus, the development of new therapies is urgently needed. Qualified animal models of COPD could help to characterize the underlying mechanisms and can be used for new drug screening. Current COPD models, such as lipopolysaccharide (LPS) or the porcine pancreatic elastase (PPE)-induced emphysema model, generate COPD-like lesions in the lungs and airways but do not otherwise resemble the pathogenesis of human COPD. A cigarette smoke (CS)-induced model remains one of the most popular because it not only simulates COPD-like lesions in the respiratory system, but it is also based on one of the main hazardous materials that causes COPD in humans. However, the time-consuming and labor-intensive aspects of the CS-induced model dramatically limit its application in new drug screening. In this study, we successfully generated a new COPD model by exposing mice to high levels of ozone. This model demonstrated the following: 1) decreased forced expiratory volume 25, 50, and 75/forced vital capacity (FEV25/FVC, FEV50/FVC, and FEV75/FVC), indicating the deterioration of lung function; 2) enlarged lung alveoli, with lung parenchymal destruction; 3) reduced fatigue time and distance; and 4) increased inflammation. Taken together, these data demonstrate that the ozone exposure (OE) model is a reliable animal model that is similar to humans because ozone overexposure is one of the etiological factors of COPD. Additionally, it only took 6 - 8 weeks, based on our previous work, to create an OE model, whereas it requires 3 - 12 months to induce the cigarette smoke model, indicating that the OE model might be a good choice for COPD research.

This study describes the successful generation of a new chronic obstructive pulmonary disease (COPD) animal model by repeatedly exposing mice to high concentrations of ozone.

反复臭氧暴露对小鼠慢性阻塞性肺疾病模型的产生

Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation and lung parenchymal destruction. It has a very high ...

Acupoint Needle-Embedding Combined with Ironing Therapy for Postoperative Pain After Anal Surgery

Acupoint needle-embedding combined with ironing therapy is a non-drug treatment method to release postoperative pain after anal surgery. The practice is guided by traditional Chinese medicine (TCM) syndrome differentiation theory and employs acupoint stimulation and heat to alleviate pain. Although prior research has shown that these are dependable methods for pain relief, the combined effect of the two techniques has not been described. In our research, we found that compared to using diclofenac sodium enteric-coated capsules alone, adding acupoint needle-embedding combined with ironing therapy was more effective for reducing pain levels at different stages after hemorrhoid surgery. Although this technique is efficient and commonly used in clinics, due to its invasive practice, acupoint needle embedding still carries risks relating to hospital-acquired infections and broken needles. Ironing therapy, on the other hand, can result in burns and connective tissue injuries. Therefore, there is an urgent need to develop a standardized protocol for medical staff. Our protocol refines the traditional techniques and provides detailed instructions on patient preparation, operation techniques, and postoperative care to ensure the therapy is carried out safely and efficiently. By standardizing this therapy, this technique is expected to become an important complementary therapy for postoperative pain relief&#160;in hemorrhoids, which will significantly improve patients &#39;life quality after anal surgery.

The high incidence of pain after anal surgery is due to the physiological structure and pathological status of the anus. At present, the use of painkillers cannot provide satisfactory pain relief, which makes complementary therapy important. This paper proposes acupoint needle-embedding combined with ironing therapy to relieve postoperative pain.

穴位嵌入联合熨烫治疗肛门术后疼痛

Acupoint needle-embedding combined with ironing therapy is a non-drug treatment method to release postoperative pain after anal surgery. The practice is ...

用耳石膏治疗妊娠呕吐

Ear Plaster Therapy as a Safe and Effective Treatment for Gestational Vomiting

Nausea and vomiting in pregnancy (NVP) are common symptoms that often complicate early pregnancy for many women. While clinical treatments such as fasting, fluid infusion, and nutritional support are conventionally applied to manage NVP, their effectiveness varies. However, traditional ear plaster therapy offers a promising alternative that effectively relieves symptoms and poses no known risk to the development of embryos or fetuses. This therapy is known for its ease of application, cost-effectiveness, and favorable outcomes. Previous studies have demonstrated the efficacy of combining ear plaster therapy with conventional treatments in alleviating symptoms of nausea and vomiting in pregnant women, surpassing the results achieved with conventional treatment alone. The protocol presented herein describes a method to relieve NVP using round, smooth, and hard cowherb seeds applied to specific ear points. These seeds are gently rubbed onto the surface of the ear, utilizing the principles of acupressure. By stimulating the designated ear points, this procedure aims to regulate the body's energy flow and restore balance, thereby reducing the severity and frequency of NVP. The application of cowherb seeds on specific ear points is a straightforward technique that healthcare professionals can easily implement or self-administered by pregnant women under appropriate guidance. Overall, ear plaster therapy presents a safe, effective, and economical approach for managing gestational vomiting, offering women a potential solution to alleviate their discomfort during pregnancy.

作者聚焦：通过安全有效的耳针缓解怀孕期间的恶心和呕吐 

The presented protocol describes a traditional Chinese medicine treatment procedure known for its safety and effectiveness in managing gestational vomiting.

耳膏疗法是一种安全有效的妊娠呕吐治疗方法

Nausea and vomiting in pregnancy (NVP) are common symptoms that often complicate early pregnancy for many women. While clinical treatments such as ...

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a common and frequent disease in elderly patients, with a tendency for progressive exacerbation. Constipation that reduces the quality of life and triggers the risk of diseases is a common concomitant symptom in patients with COPD. Currently, western medical treatment does not achieve the desired results for patients. A high recurrence rate accompanies it, whereas traditional Chinese medicine (TCM) has a long history and rich experience in treating chronic diseases. Both acupoint application and acupoint massage are characteristic therapies of TCM, with minor side effects, high safety, simple operation, and outstanding advantages. They are effective in treating constipation for patients with COPD and are considered an ideal alternative therapy for patients with chronic constipation. The purpose of this article is to introduce the method of acupoint application combined with acupoint massage for the treatment of constipation in patients with COPD, including the selection of points, items, treatment time, and operation procedure.

Here we demonstrate acupoint application combined with acupoint massage for treating constipation in a patient with chronic obstructive pulmonary disease (COPD).

穴位应用联合穴位按摩治疗慢性阻塞性肺疾病患者便秘

Chronic obstructive pulmonary disease (COPD) is a common and frequent disease in elderly patients, with a tendency for progressive exacerbation. ...

针灸刺激耳朵以缓解 COPD 患者的睡眠障碍

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

Chronic obstructive pulmonary disease (COPD) is a clinical syndrome characterized by persistent and irreversible airflow limitation and chronic respiratory symptoms. It has a wide spectrum of complications, and sleep disorders, as part of it, are common in severe cases, especially in elderly patients. Long-term lack of sleep may lead to the aggravation of the original disease, reducing patients' quality of life. Benzodiazepines are mainly used for symptomatic treatment of COPD combined with sleep disorders. However, such drugs have the side effect of respiratory central inhibition and could probably aggravate hypoxia symptoms. Auricular acupuncture is a special method of treating physical and psychosomatic dysfunctions by stimulating specific points in the ear. This article explains the specific methods of clinical operation of auricular acupuncture in detail, including assessment of patient eligibility, medical devices used, acupuncture points, course of treatment, post-treatment care, responses to emergencies, etc. The Pittsburgh sleep quality index (PSQI) and chronic obstructive pulmonary disease assessment scale (CAT) were used as the observational index of this method. So far, clinical reports have proved that auricular acupuncture has a definite curative effect in the treatment of COPD combined with sleep disorders, and its advantages of simple operation, few adverse reactions are worthy of further study and promotion, which provide a reference for the clinical treatment of such diseases.

作者聚焦:利用中医耳针疗法改善睡眠障碍 

This protocol introduces an effective method to improve the sleep condition of patients with chronic obstructive pulmonary disease and alleviate cough symptoms by using auricular acupuncture techniques to percutaneously stimulate specific acupoints in the patients' ears.

穴位应用联合耳石膏治疗慢性阻塞性肺疾病急性加重的睡眠障碍

副本

摘要

探索更多视频

评价呼吸肌慢性脊髓损伤个人使用呼吸电机控制评估（RMCA）

反复臭氧暴露对小鼠慢性阻塞性肺疾病模型的产生

穴位嵌入联合熨烫治疗肛门术后疼痛

耳膏疗法是一种安全有效的妊娠呕吐治疗方法

耳膏疗法是一种安全有效的妊娠呕吐治疗方法

耳膏疗法是一种安全有效的妊娠呕吐治疗方法

穴位应用联合穴位按摩治疗慢性阻塞性肺疾病患者便秘

耳针作为慢性阻塞性肺疾病合并睡眠障碍的中医疗法

耳针作为慢性阻塞性肺疾病合并睡眠障碍的中医疗法

耳针作为慢性阻塞性肺疾病合并睡眠障碍的中医疗法