Patrick Doherty

Is cardiac rehabilitation still relevant in the new millennium?

Dimeric versions of two short N-cadherin binding motifs (HAVDI and INPISG) function as N-cadherin agonists.

An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling.

Direct measurement of local raised subplasmalemmal calcium concentrations in growth cones advancing on an N-cadherin substrate.

Robo1 and Robo2 are homophilic binding molecules that promote axonal growth.

The FGF receptor uses the endocannabinoid signaling system to couple to an axonal growth response.

Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain.

A dimeric version of the short N-cadherin binding motif HAVDI promotes neuronal cell survival by activating an N-cadherin/fibroblast growth factor receptor signalling cascade.

Neuroglian and FasciclinII can promote neurite outgrowth via the FGF receptor Heartless.

Cannabinoid receptor, CB1, expression follows neuronal differentiation in the early chick embryo.

Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs.

Overcoming the inhibitors of myelin with a novel neurotrophin strategy.

A complementary peptide approach applied to the design of novel semaphorin/neuropilin antagonists.

Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis.

The fibroblast growth factor receptor acid box is essential for interactions with N-cadherin and all of the major isoforms of neural cell adhesion molecule.

Failure to validate the Health Survey for England physical activity module in a cardiac population.

Development and validation of a very brief questionnaire measure of physical activity in adults with coronary heart disease.

Heat treatment of arthroscopic knots and its effect on knot security.

Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPalpha during axonal extension in hippocampal neurons.

Tandem repeat peptide strategy for the design of neurotrophic factor mimetics.

The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation.

Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists.

A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner.

Developing research capacity in health librarians: a review of the evidence.

Wiring and firing neuronal networks: endocannabinoids take center stage.

Investigation of growth, development, and factors associated with injury in elite schoolboy footballers: prospective study.

Randomized controlled trial of effectiveness of pedometers on general practitioners' attitudes to engagement in and promotion of physical activity.

Acquisition of a time-memory in forager honey bees.

Receptors for myelin inhibitors: Structures and therapeutic opportunities.

Down-regulation of diacylglycerol lipase-alpha during neural stem cell differentiation: identification of elements that regulate transcription.

A retinoic acid receptor beta agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord.

BDNF regulates neuronal sensitivity to endocannabinoids.

Overcoming amino-Nogo-induced inhibition of cell spreading and neurite outgrowth by 12-O-tetradecanoylphorbol-13-acetate-type tumor promoters.

The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain.

Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice.

Amphotericin B, identified from a natural product screen, antagonizes CNS inhibitors to promote axon growth via activation of an Akt pathway in neurons.

Reliability of a two-dimensional footprint measurement approach.

The long-term benefits of cardiac rehabilitation on depression, anxiety, physical activity and quality of life.

Endocannabinoids regulate the migration of subventricular zone-derived neuroblasts in the postnatal brain.

Can level of education, accreditation and use of databases in cardiac rehabilitation be improved? Results from the European Cardiac Rehabilitation Inventory Survey.

Involving primary care and cardiac rehabilitation in a reorganised service could improve outcomes.

Long-term cardiovascular conditions: the role of primary care.

Response to Ski CF & Thompson DR (2011) Commentary on Yohannes AM, Doherty P, Bundy C & Yalfani A (2010) The long-term benefits of cardiac rehabilitation on depression, anxiety, physical activity and quality of life. Journal of Clinical Nursing 19, 2806-2813.

DAGL-dependent endocannabinoid signalling: roles in axonal pathfinding, synaptic plasticity and adult neurogenesis.

Estimation of stature from static and dynamic footprints.

The RAMIT trial, a pragmatic RCT of cardiac rehabilitation versus usual care: what does it tell us?

Effects of exercise training for heart failure with preserved ejection fraction: a systematic review and meta-analysis of comparative studies.

Amyloid precursor protein (APP) contributes to pathology in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

Secondary prevention in the clinical management of patients with cardiovascular diseases. Core components, standards and outcome measures for referral and delivery.

Competing time-to-event endpoints in cardiology trials: A simulation study to illustrate the importance of an adequate statistical analysis.

The molecular basis of the cooperation between EGF, FGF and eCB receptors in the regulation of neural stem cell function.

The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling.

Guided gingival fibroblast attachment to titanium surfaces: an in vitro study.

The effect of referral for cardiac rehabilitation on survival following acute myocardial infarction: a comparison survival in two cohorts collected in 1995 and 2003.

Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons.

BACPR scientific statement: British standards and core components for cardiovascular disease prevention and rehabilitation.

Cardiac rehabilitation mortality trends: how far from a true picture are we?

Cardiac rehabilitation and mortality reduction after myocardial infarction: the emperor's new clothes? Evidence in favour of cardiac rehabilitation.

Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling.

Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides.

Fascin regulates the migration of subventricular zone-derived neuroblasts in the postnatal brain.