Alfons Lawen

Cyclosporin A, FK506 and rapamycin produce multiple, temporally distinct, effects on memory following single-trial, passive avoidance training in the chick.

Mapping and molecular modeling of S-adenosyl-L-methionine binding sites in N-methyltransferase domains of the multifunctional polypeptide cyclosporin synthetase.

Transplasma membrane electron transport: enzymes involved and biological function.

Photoaffinity labeling of the N-methyltransferase domains of cyclosporin synthetase.

New functions of an old protein: the eukaryotic porin or voltage dependent anion selective channel (VDAC).

Involvement of reactive oxygen species in capsaicinoid-induced apoptosis in transformed cells.

Apoptosis-an introduction.

Novel effects on memory observed following unilateral intracranial administration of okadaic acid, cyclosporin A, FK506 and [MeVal4]CyA.

VDAC1 is a transplasma membrane NADH-ferricyanide reductase.

Bioethics needs a distinct voice if it is to aid science.

Non-ribosomal peptide synthetases as technological platforms for the synthesis of highly modified peptide bioeffectors--Cyclosporin synthetase as a complex example.

Voltage-dependent anion-selective channel 1 (VDAC1)--a mitochondrial protein, rediscovered as a novel enzyme in the plasma membrane.

Characterization of VDAC1 as a plasma membrane NADH-oxidoreductase.

Plasma membrane NADH-oxidoreductase in cells carrying mitochondrial DNA G11778A mutation and in cells devoid of mitochondrial DNA (rho0).

An improved purification procedure for cyclosporin synthetase.

Another piece of the puzzle of apoptotic cytochrome c release.

A highly sensitive colorimetric microplate ferrocyanide assay applied to ascorbate-stimulated transplasma membrane ferricyanide reduction and mitochondrial succinate oxidation.

Mitocans: mitochondrial targeted anti-cancer drugs as improved therapies and related patent documents.

Non-transferrin iron reduction and uptake are regulated by transmembrane ascorbate cycling in K562 cells.

Targeting mitochondrial permeability in cancer drug development.

Ascorbate and plasma membrane electron transport--enzymes vs efflux.

Transplasma membrane electron transport comes in two flavors.

Inhibition of Abeta aggregation and neurotoxicity by the 39-kDa receptor-associated protein.

Voltage-dependent anion-selective channel (VDAC) in the plasma membrane.

A role for Na+/H+ exchangers and intracellular pH in regulating vitamin C-driven electron transport across the plasma membrane.

Neurones express glutamine synthetase when deprived of glutamine or interaction with astrocytes.

Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron.

Characterization of the N-methyltransferase activities of the multifunctional polypeptide cyclosporin synthetase.

The glutamate aspartate transporter (GLAST) mediates L-glutamate-stimulated ascorbate-release via swelling-activated anion channels in cultured neonatal rodent astrocytes.

Mammalian iron homeostasis in health and disease: uptake, storage, transport, and molecular mechanisms of action.