Christopher Porter

Evaluation of the in-vitro digestion profiles of long and medium chain glycerides and the phase behaviour of their lipolytic products.

Cutaneous leiomyosarcoma.

A physicochemical basis for the extensive intestinal lymphatic transport of a poorly lipid soluble antimalarial, halofantrine hydrochloride, after postprandial administration to dogs.

Systematic evaluation of map quality: human chromosome 22.

Arab genetic disease database (AGDDB): a population-specific clinical and mutation database.

Structural contingency theory and individual differences: examination of external and internal person-team fit.

Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats.

Predicting the outcome of prostate biopsy in a racially diverse population: a prospective study.

Role of advanced 2 and 3-dimensional ultrasound for detecting prostate cancer.

Influenza immunization practices among pediatric oncologists.

Separation and characterization of the colloidal phases produced on digestion of common formulation lipids and assessment of their impact on the apparent solubility of selected poorly water-soluble drugs.

Desbutylhalofantrine: evaluation of QT prolongation and other cardiovascular effects after intravenous administration in vivo.

An in vitro examination of the impact of polyethylene glycol 400, Pluronic P85, and vitamin E d-alpha-tocopheryl polyethylene glycol 1000 succinate on P-glycoprotein efflux and enterocyte-based metabolism in excised rat intestine.

A kinetic evaluation of the absorption, efflux, and metabolism of verapamil in the autoperfused rat jejunum.

Does stereoselective lymphatic absorption contribute to the enantioselective pharmacokinetics of halofantrine In Vivo?

Using the polymer partitioning method to probe the thermodynamic activity of poorly water-soluble drugs solubilized in model lipid digestion products.

Contribution of lymphatically transported testosterone undecanoate to the systemic exposure of testosterone after oral administration of two andriol formulations in conscious lymph duct-cannulated dogs.

Backing up behaviors in teams: the role of personality and legitimacy of need.

Application of compartmental modeling to an examination of in vitro intestinal permeability data: assessing the impact of tissue uptake, P-glycoprotein, and CYP3A.

Pharmacokinetic model to describe the lymphatic absorption of r-metHu-leptin after subcutaneous injection to sheep.

Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides.

Team learning: collectively connecting the dots.

Conscientiousness, autonomy fit, and development: a longitudinal study.

Intestinal lymphatic transport of halofantrine occurs after oral administration of a unit-dose lipid-based formulation to fasted dogs.

Urothelial neoplasms of the kidney and ureter. An epidemiologic, pathologic, and clinical review.

Combining artificial neural networks and transrectal ultrasound in the diagnosis of prostate cancer.

Probing drug solubilization patterns in the gastrointestinal tract after administration of lipid-based delivery systems: a phase diagram approach.

Low AUA symptom score independently predicts positive prostate needle biopsy: results from a racially diverse series of 411 patients.

Immune responses to influenza immunization in children receiving maintenance chemotherapy for acute lymphoblastic leukemia.

Pharmacokinetics of recombinant human leukemia inhibitory factor in sheep.

Evaluation of the impact of altered lipoprotein binding conditions on halofantrine induced QTc interval prolongation in an anaesthetized rabbit model.

Influence of physicochemical properties on the patterns of association of a series of aliphatic esters of halofantrine with plasma lipoproteins.

Drug solubilization behavior during in vitro digestion of simple triglyceride lipid solution formulations.

Drug solubilization behavior during in vitro digestion of suspension formulations of poorly water-soluble drugs in triglyceride lipids.

Ultrasonic spectrum-analysis and neural-network classification as a basis for ultrasonic imaging to target brachytherapy of prostate cancer.

Use of in vitro lipid digestion data to explain the in vivo performance of triglyceride-based oral lipid formulations of poorly water-soluble drugs: studies with halofantrine.

Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation.

A novel cubic phase of medium chain lipid origin for the delivery of poorly water soluble drugs.

Lymphatic absorption is the primary contributor to the systemic availability of epoetin Alfa following subcutaneous administration to sheep.

Influence of the intermediate digestion phases of common formulation lipids on the absorption of a poorly water-soluble drug.

Necrotising fasciitis and cellulitis after traditional Samoan tattooing: case reports.

The interaction of lipophilic drugs with intestinal fatty acid-binding protein.

Recent developments in tissue-type imaging (TTI) for planning and monitoring treatment of prostate cancer.

Study of stem cell function using microarray experiments.

Congenital auricular anomalies: topographic anatomy, embryology, classification, and treatment strategies.

Model to predict prostate biopsy outcome in large screening population with independent validation in referral setting.

An improved method for the purification of rat liver-type fatty acid binding protein from Escherichia coli.

Absence of lower urinary tract symptoms is an independent predictor for cancer at prostate biopsy, but prostate-specific antigen is not: results from a prospective series of 569 patients.

Increasing the number of biopsy cores improves the concordance of biopsy Gleason score to prostatectomy Gleason score.

Goal orientation: effects on backing up behavior, performance, efficacy, and commitment in teams.

Bile increases intestinal lymphatic drug transport in the fasted rat.

Tissue uptake of DDT is independent of chylomicron metabolism.

The lymph lipid precursor pool is a key determinant of intestinal lymphatic drug transport.

Impaired DNA replication within progenitor cell pools promotes leukemogenesis.

An examination of the interplay between enterocyte-based metabolism and lymphatic drug transport in the rat.

Prostate specific antigen remains an independent predictor of cancer at prostate biopsy in black american men but not in white men: results from a consecutive series of 914 men.

Examination of the impact of a range of Pluronic surfactants on the in-vitro solubilisation behaviour and oral bioavailability of lipidic formulations of atovaquone.

An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.

25-year prostate cancer control and survival outcomes: a 40-year radical prostatectomy single institution series.

An acute and coincident increase in FABP expression and lymphatic lipid and drug transport occurs during intestinal infusion of lipid-based drug formulations to rats.

Permeability assessment of poorly water-soluble compounds under solubilizing conditions: the reciprocal permeability approach.

Distortion-product otoacoustic emission suppression growth in normal and noise-exposed rabbits.

The absorption of darbepoetin alfa occurs predominantly via the lymphatics following subcutaneous administration to sheep.

Cationic poly-L-lysine dendrimers: pharmacokinetics, biodistribution, and evidence for metabolism and bioresorption after intravenous administration to rats.

Development and external validation of an extended 10-core biopsy nomogram.

Treatment of upper tract urothelial carcinoma: a review of surgical and adjuvant therapy.

Impact of cremophor-EL and polysorbate-80 on digoxin permeability across rat jejunum: delineation of thermodynamic and transporter related events using the reciprocal permeability approach.

Prostate cancer-specific survival in men treated with hormonal therapy after failure of radical prostatectomy.

An abnormal digital rectal examination is an independent predictor of Gleason > or =7 prostate cancer in men undergoing initial prostate biopsy: a prospective study of 790 men.

Development and external validation of an extended repeat biopsy nomogram.

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.

Posttransplant Hodgkin lymphoma preceded by polymorphic posttransplant lymphoproliferative disorder: report of a pediatric case and review of the literature.

Does the number of prostate biopsies performed affect the nature of the cancer identified?

Experience improves staging accuracy of endorectal magnetic resonance imaging in prostate cancer: what is the learning curve?

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.

Increasing the proportional content of surfactant (Cremophor EL) relative to lipid in self-emulsifying lipid-based formulations of danazol reduces oral bioavailability in beagle dogs.

Gene function in early mouse embryonic stem cell differentiation.

Examination of the role of intestinal fatty acid-binding protein in drug absorption using a parallel artificial membrane permeability assay.

Mechanical failure rate of da Vinci robotic system.

A lipid-based liquid crystalline matrix that provides sustained release and enhanced oral bioavailability for a model poorly water soluble drug in rats.

Clinical benefits and economic analysis of pegylated liposomal doxorubicin/vincristine/dexamethasone versus doxorubicin/vincristine/dexamethasone in patients with newly diagnosed multiple myeloma.

Use of plasma proteins as solubilizing agents in in vitro permeability experiments: correction for unbound drug concentration using the reciprocal permeability approach.

Low dose lipid formulations: effects on gastric emptying and biliary secretion.

How useful is PSA velocity as a screening tool for prostate cancer detection?

ChIP on SNP-chip for genome-wide analysis of human histone H4 hyperacetylation.

Lymphatic absorption of subcutaneously administered proteins: influence of different injection sites on the absorption of darbepoetin alfa using a sheep model.

Impact of surface derivatization of poly-L-lysine dendrimers with anionic arylsulfonate or succinate groups on intravenous pharmacokinetics and disposition.

Evaluation of the impact of surfactant digestion on the bioavailability of danazol after oral administration of lipidic self-emulsifying formulations to dogs.

Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies.

Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update.

Enhancing intestinal drug solubilisation using lipid-based delivery systems.

Lipid-based systems for the enhanced delivery of poorly water soluble drugs.

A nomogram predicting long-term biochemical recurrence after radical prostatectomy.

The impact of molecular weight and PEG chain length on the systemic pharmacokinetics of PEGylated poly l-lysine dendrimers.

StemBase: a resource for the analysis of stem cell gene expression data.

Characterization of the drug binding specificity of rat liver fatty acid binding protein.

Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection.

A nomogram predicting metastatic progression after radical prostatectomy.

BCL6 expression correlates with monomorphic histology in children with posttransplantation lymphoproliferative disease.

An evaluation of the relative roles of the unstirred water layer and receptor sink in limiting the in-vitro intestinal permeability of drug compounds of varying lipophilicity.

Vincristine induced peripheral neuropathy potentiated by voriconazole in a patient with previously undiagnosed CMT1X.

Seeing is believing.

Adjuvant radiotherapy after radical prostatectomy shows no ability to improve rates of overall and cancer-specific survival in a matched case-control study.

Phase II trial of neoadjuvant docetaxel and gefitinib followed by radical prostatectomy in patients with high-risk, locally advanced prostate cancer.

Characterization of lipophilic drug binding to rat intestinal fatty acid binding protein.

Intestinal lymphatic transport enhances the post-prandial oral bioavailability of a novel cannabinoid receptor agonist via avoidance of first-pass metabolism.

Recent developments in StemBase: a tool to study gene expression in human and murine stem cells.

Management of non-germinal testicular tumors.

Pharmacokinetics and tumor disposition of PEGylated, methotrexate conjugated poly-l-lysine dendrimers.

Solution characterization of the extracellular region of CD147 and its interaction with its enzyme ligand cyclophilin A.

Oral bioavailability assessment and intestinal lymphatic transport of Org 45697 and Org 46035, two highly lipophilic novel immunomodulator analogues.

Probing the fibrate binding specificity of rat liver fatty acid binding protein.

PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats.

Lymphatic transport of Methylnortestosterone undecanoate (MU) and the bioavailability of methylnortestosterone are highly sensitive to the mass of coadministered lipid after oral administration of MU.

Radical retropubic cystectomy.

MRI after technically successful renal cryoablation: early contrast enhancement as a common finding.

Irradiation selects for p53-deficient hematopoietic progenitors.

A nomogram predicting prostate cancer-specific mortality after radical prostatectomy.

The role of the intestinal lymphatics in the absorption of two highly lipophilic cholesterol ester transfer protein inhibitors (CP524,515 and CP532,623).

The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response.

Genomic predictors of prostate cancer therapy outcomes.

The mechanism of lymphatic access of two cholesteryl ester transfer protein inhibitors (CP524,515 and CP532,623) and evaluation of their impact on lymph lipoprotein profiles.

Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water soluble drugs I. Phase behaviour in physiologically-relevant media.

Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water-soluble drugs II. In-vivo evaluation.

When goal orientations collide: effects of learning and performance orientation on team adaptability in response to workload imbalance.

Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?

Using polymeric precipitation inhibitors to improve the absorption of poorly water-soluble drugs: A mechanistic basis for utility.

Does a perioperative belladonna and opium suppository improve postoperative pain following robotic assisted laparoscopic radical prostatectomy? Results of a single institution randomized study.

Capping methotrexate α-carboxyl groups enhances systemic exposure and retains the cytotoxicity of drug conjugated PEGylated polylysine dendrimers.

Characterisation and tumour targeting of PEGylated polylysine dendrimers bearing doxorubicin via a pH labile linker.

Ultrasound-guided thoracic facet injections: description of a technique.

Quantitative ultrasound in cancer imaging.

Nanostructured liquid crystalline particles provide long duration sustained-release effect for a poorly water soluble drug after oral administration.

The association between pre-operative PSA and prostate cancer-specific mortality in patients with long-term follow-up after radical prostatectomy.

Fatty acid binding proteins: potential chaperones of cytosolic drug transport in the enterocyte?

Acute hypertriglyceridemia promotes intestinal lymphatic lipid and drug transport: a positive feedback mechanism in lipid and drug absorption.

Targeting the lymphatics using dendritic polymers (dendrimers).

A comparison of changes to doxorubicin pharmacokinetics, antitumor activity, and toxicity mediated by PEGylated dendrimer and PEGylated liposome drug delivery systems.

Differences in colloidal structure of PEGylated nanomaterials dictate the likelihood of accelerated blood clearance.

Incidence of second malignancies after external beam radiotherapy for clinical stage I testicular seminoma.

The long-term outcomes after radical prostatectomy of patients with pathologic Gleason 8-10 disease.

Dendrimer pharmacokinetics: the effect of size, structure and surface characteristics on ADME properties.

Correction to "targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?".

The history and anatomy of urologic lymphadenectomy.

Racial/Ethnic patterns in prostate cancer outcomes in an active surveillance cohort.

Doxorubicin-Conjugated PEGylated Dendrimers Show Similar Tumoricidal Activity but Lower Systemic Toxicity When Compared to PEGylated Liposome and Solution Formulations in Mouse and Rat Tumor Models.

Association of Chemotherapeutic Drugs with Dendrimer Nanocarriers: An Assessment of the Merits of Covalent Conjugation Compared to Noncovalent Encapsulation.