Lineberger Comprehensive Cancer Center,
Division of Neuropathology,
Department of Pathology and Laboratory Medicine,
Department of Neurology,
Neurosciences Center,
Division of Neuropathology, Department of Pathology and Laboratory Medicine,
Department of Neurology, Neurosciences Center
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Quantitation of cytosine deaminase mRNA by real-time reverse transcription polymerase chain reaction: a sensitive method for assessing 5-fluorocytosine toxicity in vitro.
Analytical biochemistry Feb, 2002 | Pubmed ID: 11814289
Intratumoral 5-fluorouracil produced by cytosine deaminase/5-fluorocytosine gene therapy is effective for experimental human glioblastomas.
Cancer research Feb, 2002 | Pubmed ID: 11830532
Induction of thymidine phosphorylase in both irradiated and shielded, contralateral human U87MG glioma xenografts: implications for a dual modality treatment using capecitabine and irradiation.
Molecular cancer therapeutics Oct, 2002 | Pubmed ID: 12481438
Delta24-hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization.
Cancer gene therapy Mar, 2005 | Pubmed ID: 15650766
Significance of necrosis in grading of oligodendroglial neoplasms: a clinicopathologic and genetic study of newly diagnosed high-grade gliomas.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Dec, 2006 | Pubmed ID: 17135643
Pharmacogenomics of cancer chemotherapy-induced toxicity.
The journal of supportive oncology Jan, 2007 | Pubmed ID: 17265780
Glioblastoma.
Archives of pathology & laboratory medicine Mar, 2007 | Pubmed ID: 17516742
A clinical model to estimate recurrence risk in resected stage I non-small cell lung cancer.
American journal of clinical oncology Feb, 2008 | Pubmed ID: 18376223
Malignant gliomas with primitive neuroectodermal tumor-like components: a clinicopathologic and genetic study of 53 cases.
Brain pathology (Zurich, Switzerland) Jan, 2009 | Pubmed ID: 18452568
Risk of recurrence of resected stage I non-small cell lung cancer in elderly patients as compared with younger patients.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer Nov, 2009 | Pubmed ID: 19692932
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.
Cancer cell Jan, 2010 | Pubmed ID: 20129251
Lung squamous cell carcinoma mRNA expression subtypes are reproducible, clinically important, and correspond to normal cell types.
Clinical cancer research : an official journal of the American Association for Cancer Research Oct, 2010 | Pubmed ID: 20643781
Tryptase staining of mast cells may differentiate eosinophilic esophagitis from gastroesophageal reflux disease.
The American journal of gastroenterology Feb, 2011 | Pubmed ID: 20978486
Gone FISHing: clinical lessons learned in brain tumor molecular diagnostics over the last decade.
Brain pathology (Zurich, Switzerland) Jan, 2011 | Pubmed ID: 21129060
The prognostic contribution of clinical breast cancer subtype, age, and race among patients with breast cancer brain metastases.
Cancer Apr, 2011 | Pubmed ID: 21472708
Genetically engineered mouse models of diffuse gliomas.
Brain research bulletin May, 2012 | Pubmed ID: 21684324
High XRCC1 protein expression is associated with poorer survival in patients with head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research Oct, 2011 | Pubmed ID: 21908577
Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.
Breast cancer research : BCR , 2011 | Pubmed ID: 22132754
RhoGDI2 antagonizes ovarian carcinoma growth, invasion and metastasis.
Small GTPases 7, 2011 | Pubmed ID: 22145092
An animal model of MYC-driven medulloblastoma.
Cancer cell Feb, 2012 | Pubmed ID: 22340590
Validation of Interobserver Agreement in Lung Cancer Assessment Hematoxylin-Eosin Diagnostic Reproducibility for Non-Small Cell Lung Cancer-The 2004 World Health Organization Classification and Therapeutically Relevant Subsets.
Archives of pathology & laboratory medicine May, 2012 | Pubmed ID: 22583114
Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation.
PloS one , 2012 | Pubmed ID: 22590557
LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma.
Cancer cell Jun, 2012 | Pubmed ID: 22698401
Diagnostic utility of major basic protein, eotaxin-3, and leukotriene enzyme staining in eosinophilic esophagitis.
The American journal of gastroenterology Oct, 2012 | Pubmed ID: 22777338
Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer.
Nature communications , 2013 | Pubmed ID: 23385593
Histological predictors of outcome in ependymoma are dependent on anatomic site within the central nervous system.
Brain pathology (Zurich, Switzerland) Sep, 2013 | Pubmed ID: 23452038
HIF1α and HIF2α independently activate SRC to promote melanoma metastases.
The Journal of clinical investigation May, 2013 | Pubmed ID: 23563312
MERTK receptor tyrosine kinase is a therapeutic target in melanoma.
The Journal of clinical investigation May, 2013 | Pubmed ID: 23585477
Pharmacokinetics and efficacy of PEGylated liposomal doxorubicin in an intracranial model of breast cancer.
PloS one , 2013 | Pubmed ID: 23650496
Prediction of lung cancer histological types by RT-qPCR gene expression in FFPE specimens.
The Journal of molecular diagnostics : JMD Jul, 2013 | Pubmed ID: 23701907
Cooperativity between MAPK and PI3K signaling activation is required for glioblastoma pathogenesis.
Neuro-oncology Oct, 2013 | Pubmed ID: 23814263
Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2013 | Pubmed ID: 23864165
Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma.
Cancer & metabolism Jan, 2013 | Pubmed ID: 24078863
Evolutionary etiology of high-grade astrocytomas.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2013 | Pubmed ID: 24114272
αB-crystallin: a novel regulator of breast cancer metastasis to the brain.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2014 | Pubmed ID: 24132917
Cerebellar granule neuron progenitors are the source of Hk2 in the postnatal cerebellum.
Cancer & metabolism , 2013 | Pubmed ID: 24280296
Hexokinase-2-mediated aerobic glycolysis is integral to cerebellar neurogenesis and pathogenesis of medulloblastoma.
Cancer & metabolism , 2013 | Pubmed ID: 24280485
Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure (ABC2) low-grade glioma research workshop.
Neuro-oncology Jan, 2014 | Pubmed ID: 24305708
Development of DNA damage response signaling biomarkers using automated, quantitative image analysis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society Mar, 2014 | Pubmed ID: 24309508
The Role of Ect2 Nuclear RhoGEF Activity in Ovarian Cancer Cell Transformation.
Genes & cancer Nov, 2013 | Pubmed ID: 24386507
Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal.
The Journal of clinical investigation Feb, 2014 | Pubmed ID: 24435044
ClearCode34: A prognostic risk predictor for localized clear cell renal cell carcinoma.
European urology Jul, 2014 | Pubmed ID: 24613583
Robert S. McNeill1,
Ralf S. Schmid2,
Ryan E. Bash3,
Mark Vitucci4,
Kristen K. White1,
Andrea M. Werneke3,
Brian H. Constance5,
Byron Huff6,
C. Ryan Miller2,3,7
1Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine,
2Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine,
3Division of Neuropathology, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine,
4Curriculum in Genetics and Molecular Biology, University of North Carolina School of Medicine,
5Biological and Biomedical Sciences Program, University of North Carolina School of Medicine,
6Department of Radiation Oncology, Emory University School of Medicine,
7Department of Neurology, Neurosciences Center, University of North Carolina School of Medicine
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