Hogune Im

dELL, a drosophila homologue of transcription elongation factor ELL (Eleven-nineteen Lysine rich Leukemia), is required for early development.

Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain.

Dynamic regulation of histone H3 methylated at lysine 79 within a tissue-specific chromatin domain.

Highly restricted localization of RNA polymerase II within a locus control region of a tissue-specific chromatin domain.

Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation.

Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region.

Establishment and regulation of chromatin domains: mechanistic insights from studies of hemoglobin synthesis.

H3 K79 dimethylation marks developmental activation of the beta-globin gene but is reduced upon LCR-mediated high-level transcription.

Global identification of protein kinase substrates by protein microarray analysis.

Personal omics profiling reveals dynamic molecular and medical phenotypes.

A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17.

Identification of potential glycan cancer markers with sialic acid attached to sialic acid and up-regulated fucosylated galactose structures in epidermal growth factor receptor secreted from A431 cell line.

Preparation of recombinant protein spotted arrays for proteome-wide identification of kinase targets.

Genome wide proteomics of ERBB2 and EGFR and other oncogenic pathways in inflammatory breast cancer.

Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias.

Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes.

Specific plasma autoantibody reactivity in myelodysplastic syndromes.

Whole-Exome Enrichment with the Agilent SureSelect Human All Exon Platform.

Whole-Exome Enrichment with the Illumina TruSeq Exome Enrichment Platform.

Whole-Exome Enrichment with the Roche NimbleGen SeqCap EZ Exome Library SR Platform.

RNAseq Reveals a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension.