Francesco Cardarelli

Development of a novel GFP-based ratiometric excitation and emission pH indicator for intracellular studies.

In vivo study of HIV-1 Tat arginine-rich motif unveils its transport properties.

Tuning the transport properties of HIV-1 Tat arginine-rich motif in living cells.

Real-time measurement of endosomal acidification by a novel genetically encoded biosensor.

Probing nuclear localization signal-importin alpha binding equilibria in living cells.

Quantitative analysis of Tat peptide binding to import carriers reveals unconventional nuclear transport properties.

Fluorescent recovery after photobleaching (FRAP) analysis of nuclear export rates identifies intrinsic features of nucleocytoplasmic transport.

Intact microtubules preserve transient receptor potential vanilloid 1 (TRPV1) functionality through receptor binding.

Fluorescence recovery after photobleaching reveals the biochemistry of nucleocytoplasmic exchange.

A novel chimeric cell-penetrating peptide with membrane-disruptive properties for efficient endosomal escape.

Unveiling LOX-1 receptor interplay with nanotopography: mechanotransduction and atherosclerosis onset.

Imaging intracellular viscosity by a new molecular rotor suitable for phasor analysis of fluorescence lifetime.

Fast spatiotemporal correlation spectroscopy to determine protein lateral diffusion laws in live cell membranes.

In Vitro Efficient Transfection by CM18-Tat11 Hybrid Peptide: A New Tool for Gene-Delivery Applications.

Antimicrobial peptides design by evolutionary multiobjective optimization.

High-yield nontoxic gene transfer through conjugation of the CM₁₈-Tat₁₁ chimeric peptide with nanosecond electric pulses.

Nanoscale protein diffusion by STED-based pair correlation analysis.

Mechanistic insight into CM18-Tat11 peptide membrane-perturbing action by whole-cell patch-clamp recording.

Probing short-range protein Brownian motion in the cytoplasm of living cells.

Unveiling TRPV1 spatio-temporal organization in live cell membranes.

Spontaneous membrane-translocating peptides: influence of peptide self-aggregation and cargo polarity.

Single-cell real-time imaging of transgene expression upon lipofection.

Spatiotemporal Fluctuation Analysis: A Powerful Tool for the Future Nanoscopy of Molecular Processes.

Diffusion Tensor Analysis by Two-Dimensional Pair Correlation of Fluorescence Fluctuations in Cells.

Measurement of nanoscale three-dimensional diffusion in the interior of living cells by STED-FCS.

Self-aggregation propensity of the Tat peptide revealed by UV-Vis, NMR and MD analyses.

The role of Tat peptide self-aggregation in membrane pore stabilization: insights from a computational study.

Dynamic fingerprinting of sub-cellular nanostructures by image mean square displacement analysis.

Spatiotemporal Fluctuation Analysis of Molecular Diffusion Laws in Live-Cell Membranes.

DPP-4 is expressed in human pancreatic beta cells and its direct inhibition improves beta cell function and survival in type 2 diabetes.

Simultaneous Detection of Local Polarizability and Viscosity by a Single Fluorescent Probe in Cells.

Human Biomolecular Corona of Liposomal Doxorubicin: The Overlooked Factor in Anticancer Drug Delivery.

Probing labeling-induced lysosome alterations in living cells by imaging-derived mean squared displacement analysis.

Probing the light scattering properties of insulin secretory granules in single live cells.

Time-lapse confocal imaging datasets to assess structural and dynamic properties of subcellular nanostructures.

Silica-Based Nanoparticles for Protein Encapsulation and Delivery.

Low-defectiveness exfoliation of MoS nanoparticles and their embedment in hybrid light-emitting polymer nanofibers.

A Synthetic Oxygen Sensor for Plants Based on Animal Hypoxia Signaling.

Capturing Metabolism-Dependent Solvent Dynamics in the Lumen of a Trafficking Lysosome.

Interplay between lipid lateral diffusion, dye concentration and membrane permeability unveiled by a combined spectroscopic and computational study of a model lipid bilayer.

Insulin secretory granules labelled with phogrin-fluorescent proteins show alterations in size, mobility and responsiveness to glucose stimulation in living β-cells.

A mechanistic explanation of the inhibitory role of the protein corona on liposomal gene expression.

Effect of Protein Corona on The Transfection Efficiency of Lipid-Coated Graphene Oxide-Based Cell Transfection Reagents.

Lysosome Dynamic Properties during Neuronal Stem Cell Differentiation Studied by Spatiotemporal Fluctuation Spectroscopy and Organelle Tracking.

A calcineurin B-like protein participates in low oxygen signalling in rice.

Back to the Future: Genetically Encoded Fluorescent Proteins as Inert Tracers of the Intracellular Environment.

Metabolic response of Insulinoma 1E cells to glucose stimulation studied by fluorescence lifetime imaging.

Mechanistic Insights into the Release of Doxorubicin from Graphene Oxide in Cancer Cells.

Synthesis, crystal structure, polymorphism and microscopic luminescence properties of anthracene derivative compounds.

PCB153 reduces apoptosis in primary cultures of murine pituitary cells through the activation of NF-κB mediated by PI3K/Akt.

Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis.

Probing the role of nuclear-envelope invaginations in the nuclear-entry route of lipofected DNA by multi-channel 3D confocal microscopy.