Jonathan P. Gumucio

Physiological loading of tendons induces scleraxis expression in epitenon fibroblasts.

Transforming growth factor-beta induces skeletal muscle atrophy and fibrosis through the induction of atrogin-1 and scleraxis.

Mechanical loading and TGF-β change the expression of multiple miRNAs in tendon fibroblasts.

Rotator cuff tear reduces muscle fiber specific force production and induces macrophage accumulation and autophagy.

Hyaluronic acid, HAS1, and HAS2 are significantly upregulated during muscle hypertrophy.

Atrogin-1, MuRF-1, and sarcopenia.

MMP inhibition as a potential method to augment the healing of skeletal muscle and tendon extracellular matrix.

Targeted inhibition of TGF-β results in an initial improvement but long term deficit in force production after contraction-induced skeletal muscle injury.

Aging-associated exacerbation in fatty degeneration and infiltration after rotator cuff tear.

Changes in macrophage phenotype and induction of epithelial-to-mesenchymal transition genes following acute Achilles tenotomy and repair.

Intrinsic stiffness of extracellular matrix increases with age in skeletal muscles of mice.

Simvastatin reduces fibrosis and protects against muscle weakness after massive rotator cuff tear.

Inhibition of 5-LOX, COX-1, and COX-2 increases tendon healing and reduces muscle fibrosis and lipid accumulation after rotator cuff repair.

Synergist ablation induces rapid tendon growth through the synthesis of a neotendon matrix.

TGF-β superfamily signaling in muscle and tendon adaptation to resistance exercise.

Changes in skeletal muscle and tendon structure and function following genetic inactivation of myostatin in rats.

p38 MAPK signaling in postnatal tendon growth and remodeling.

Haploinsufficiency of myostatin protects against aging-related declines in muscle function and enhances the longevity of mice.