Department of Medicine,
Institute for Computational Biomedicine
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Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurite outgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein.
Brain research Feb, 2002 | Pubmed ID: 11844476
Upregulation of a T-type Ca2+ channel causes a long-lasting modification of neuronal firing mode after status epilepticus.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2002 | Pubmed ID: 11978840
The role of late/slow replication of the FRA16D in common fragile site induction.
Genes, chromosomes & cancer Jan, 2004 | Pubmed ID: 14603443
High-throughput mapping of origins of replication in human cells.
EMBO reports Aug, 2007 | Pubmed ID: 17668008
Common fragile sites are characterized by histone hypoacetylation.
Human molecular genetics Dec, 2009 | Pubmed ID: 19717471
Impaired replication dynamics at the FRA3B common fragile site.
Human molecular genetics Jan, 2010 | Pubmed ID: 19815620
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation.
Science (New York, N.Y.) Aug, 2011 | Pubmed ID: 21764752
The inhibition of the pemetrexed-activated MAPK pathway via sorafenib is involved in the synergistic mechanism of sorafenib subsequent potentiation of pemetrexed cytotoxicity in EGFR TKI-resistant cell lines.
Clinical laboratory , 2012 | Pubmed ID: 22783588
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma.
PloS one , 2012 | Pubmed ID: 22808135
Nanofiber scaffolds facilitate functional regeneration of peripheral nerve injury.
Nanomedicine : nanotechnology, biology, and medicine Apr, 2013 | Pubmed ID: 22960189
Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity.
PLoS genetics , 2013 | Pubmed ID: 23326238
BCL6 breaks occur at different AID sequence motifs in Ig-BCL6 and non-Ig-BCL6 rearrangements.
Blood May, 2013 | Pubmed ID: 23476051
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.
Cancer cell May, 2013 | Pubmed ID: 23680150
Mechanisms of epigenetic deregulation in lymphoid neoplasms.
Blood May, 2013 | Pubmed ID: 23704048
A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
Nature Aug, 2013 | Pubmed ID: 23812588
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.
Cell reports Aug, 2013 | Pubmed ID: 23911289
Decreased levels of serum cytokeratin 19 fragment CYFRA 21-1 predict objective response to chemotherapy in patients with non-small cell lung cancer.
Experimental and therapeutic medicine Aug, 2013 | Pubmed ID: 24137188
Schedule-dependent synergistic interaction between docetaxel and gefitinib in NSCLC cell lines regardless of the mutation status of EGFR and KRAS and its molecular mechanisms.
Journal of cancer research and clinical oncology Jul, 2014 | Pubmed ID: 24728492
Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas.
Genome biology , 2014 | Pubmed ID: 25123191
The BCL6 RD2 domain governs commitment of activated B cells to form germinal centers.
Cell reports Sep, 2014 | Pubmed ID: 25176650
Tracing the roots of cancer evolution.
Cancer discovery Sep, 2014 | Pubmed ID: 25185189
Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.
PLoS genetics Sep, 2014 | Pubmed ID: 25188243
Lymphoblastic transformation of follicular lymphoma: a clinicopathologic and molecular analysis of 7 patients.
Human pathology Feb, 2015 | Pubmed ID: 25529125
The epigenetic basis of diffuse large B-cell lymphoma.
Seminars in hematology Apr, 2015 | Pubmed ID: 25805588
Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.
Cancer cell Apr, 2015 | Pubmed ID: 25873173
Epigenomic evolution in diffuse large B-cell lymphomas.
Nature communications , 2015 | Pubmed ID: 25891015
Multiplexing of ChIP-Seq Samples in an Optimized Experimental Condition Has Minimal Impact on Peak Detection.
PloS one , 2015 | Pubmed ID: 26066343
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.
Nature medicine Oct, 2015 | Pubmed ID: 26366710
Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma.
Genome medicine , 2015 | Pubmed ID: 26521025
The Synergistic Mechanism of Pemetrexed Followed by Kanglaite was due to KLT Subsequently Inhibiting the Pemetrexed-Activated MAPK Signaling Pathway.
Clinical laboratory , 2015 | Pubmed ID: 26642695
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