Matthias Schiemann

Reversible MHC multimer staining for functional isolation of T-cell populations and effective adoptive transfer.

Differences in maintenance of CD8+ and CD4+ bacteria-specific effector-memory T cell populations.

CpG-DNA aided cross-priming by cross-presenting B cells.

Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets.

Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes.

Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways.

Polymorphonuclear neutrophils improve replication of Chlamydia pneumoniae in vivo upon MyD88-dependent attraction.

Autoimmunity and inflammation due to a gain-of-function mutation in phospholipase C gamma 2 that specifically increases external Ca2+ entry.

Neutrophil dysfunction in guanosine 3',5'-cyclic monophosphate-dependent protein kinase I-deficient mice.

NKG2D-independent suppression of T cell proliferation by H60 and MICA.

Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo.

Unidirectional development of CD8+ central memory T cells into protective Listeria-specific effector memory T cells.

CD8alpha+ dendritic cells are required for efficient entry of Listeria monocytogenes into the spleen.

Interferon-regulatory-factor 1 controls Toll-like receptor 9-mediated IFN-beta production in myeloid dendritic cells.

Reversible HLA multimers (Streptamers) for the isolation of human cytotoxic T lymphocytes functionally active against tumor- and virus-derived antigens.

Interdependency of MHC class II/self-peptide and CD1d/self-glycolipid presentation by TNF-matured dendritic cells for protection from autoimmunity.

CD133-enriched CD34(-) (CD33/CD38/CD71)(-) cord blood cells acquire CD34 prior to cell division and hematopoietic activity is exclusively associated with CD34 expression.

Chemokine fractalkine mediates leukocyte recruitment to inflammatory endothelial cells in flowing whole blood: a critical role for P-selectin expressed on activated platelets.

Novel mouse mutants with primary cellular immunodeficiencies generated by genome-wide mutagenesis.

A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets.

Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin.

Oncostatin M-mediated regulation of KIT-ligand-induced extracellular signal-regulated kinase signaling maintains hematopoietic repopulating activity of Lin-CD34+CD133+ cord blood cells.

Stem cell-like plasticity of naïve and distinct memory CD8+ T cell subsets.

Allorestricted T lymphocytes with a high avidity T-cell receptor towards NY-ESO-1 have potent anti-tumor activity.

Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity.

Secreted frizzled-related protein 1 extrinsically regulates cycling activity and maintenance of hematopoietic stem cells.

Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors.

DCs in mouse models of intracellular bacterial infection.

Cord blood Vα24-Vβ11 natural killer T cells display a Th2-chemokine receptor profile and cytokine responses.

Identification of CCR9- murine plasmacytoid DC precursors with plasticity to differentiate into conventional DCs.

Stromal pleiotrophin regulates repopulation behavior of hematopoietic stem cells.

Different capacity of monocyte subsets to phagocytose iron-oxide nanoparticles.

Novel serial positive enrichment technology enables clinical multiparameter cell sorting.

Tissue-specific differentiation of a circulating CCR9- pDC-like common dendritic cell precursor.

Sorafenib perpetuates cellular anticancer effector functions by modulating the crosstalk between macrophages and natural killer cells.

Disparate individual fates compose robust CD8+ T cell immunity.

CXC chemokine receptor 4 is essential for maintenance of renal cell carcinoma-initiating cells and predicts metastasis.

MHC multimer-guided and cell culture-independent isolation of functional T cell receptors from single cells facilitates TCR identification for immunotherapy.

A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.

Cardioprotective C-kit⁺ bone marrow cells attenuate apoptosis after acute myocardial infarction in mice - in-vivo assessment with fluorescence molecular imaging.

Lowest numbers of primary CD8(+) T cells can reconstitute protective immunity upon adoptive immunotherapy.

Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells.

Live fluorescent RNA-based detection of pluripotency gene expression in embryonic and induced pluripotent stem cells of different species.

Myeloid zinc finger 1 (Mzf1) differentially modulates murine cardiogenesis by interacting with an Nkx2.5 cardiac enhancer.

Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity.

Genetic analysis of circulating tumor cells in pancreatic cancer patients: A pilot study.

T Cells Engineered to Express a T-Cell Receptor Specific for Glypican-3 to Recognize and Kill Hepatoma Cells In Vitro and in Mice.

Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-β Production.

Stroma-Derived Connective Tissue Growth Factor Maintains Cell Cycle Progression and Repopulation Activity of Hematopoietic Stem Cells In Vitro.