Helen May-Simera

NMDA systems in the amygdala and piriform cortex and nicotinic effects on memory function.

Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene.

Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome.

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates.

Dissection of epistasis in oligogenic Bardet-Biedl syndrome.

Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome.

Patterns of expression of Bardet-Biedl syndrome proteins in the mammalian cochlea suggest noncentrosomal functions.

Bbs8, together with the planar cell polarity protein Vangl2, is required to establish left-right asymmetry in zebrafish.

Loss of Bardet-Biedl syndrome protein-8 (BBS8) perturbs olfactory function, protein localization, and axon targeting.

Examining planar cell polarity in the mammalian cochlea.

Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis.

Planar cell polarity in the inner ear.

Cilia, Wnt signaling, and the cytoskeleton.

Bardet-Biedl syndrome proteins control the cilia length through regulation of actin polymerization.

Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton.

A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear.

Ciliopathy-associated gene Cc2d2a promotes assembly of subdistal appendages on the mother centriole during cilia biogenesis.

Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5a.

Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea.

CEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathies.

Non-essential role for cilia in coordinating precise alignment of lens fibres.