Angelika Doetzlhofer

Alternate activation of two divergently transcribed mouse genes from a bidirectional promoter is linked to changes in histone modification.

The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.

Math1-driven GFP expression in the developing nervous system of transgenic mice.

In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme.

Prospective identification and purification of hair cell and supporting cell progenitors from the embryonic cochlea.

Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells.

p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis.

Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti.

Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea.

Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling.

The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea.

Canonical Notch signaling plays an instructive role in auditory supporting cell development.