Department of Pathology and Laboratory Medicine
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The role of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in lymphoproliferative diseases.
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer , 2002 | Pubmed ID: 11785841
Human herpesvirus-8-transformed endothelial cells have functionally activated vascular endothelial growth factor/vascular endothelial growth factor receptor.
The American journal of pathology Jan, 2002 | Pubmed ID: 11786394
Epstein-Barr virus (EBV) and lymphomagenesis.
Frontiers in bioscience : a journal and virtual library Feb, 2002 | Pubmed ID: 11815280
Analysis of the human herpesvirus 8 (HHV-8) genome and HHV-8 vIL-6 expression in archival cases of castleman disease at low risk for HIV infection.
American journal of clinical pathology Feb, 2002 | Pubmed ID: 11863223
Transcriptional downregulation of ORF50/Rta by methotrexate inhibits the switch of Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 from latency to lytic replication.
Journal of virology May, 2002 | Pubmed ID: 11967335
Spectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseases.
Clinical microbiology reviews Jul, 2002 | Pubmed ID: 12097251
Human herpesvirus-8-associated lymphoma of the bowel in human immunodeficiency virus-positive patients without history of primary effusion lymphoma.
Human pathology Aug, 2002 | Pubmed ID: 12203218
The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor has broad signaling effects in primary effusion lymphoma cells.
Journal of virology Jan, 2003 | Pubmed ID: 12477810
Gene expression profile analysis of AIDS-related primary effusion lymphoma (PEL) suggests a plasmablastic derivation and identifies PEL-specific transcripts.
Blood May, 2003 | Pubmed ID: 12531789
Human immunodeficiency virus (HIV)-associated polymorphic lymphoproliferative disorders.
The American journal of surgical pathology Mar, 2003 | Pubmed ID: 12604885
Alterations of mRNA splicing in primary effusion lymphomas.
Leukemia & lymphoma May, 2003 | Pubmed ID: 12802923
Pathogenesis of Kaposi's sarcoma.
Hematology/oncology clinics of North America Jun, 2003 | Pubmed ID: 12852653
Kaposi's sarcoma-associated herpesvirus--the high cost of viral survival.
The New England journal of medicine Sep, 2003 | Pubmed ID: 13679522
KSHV vFLIP is essential for the survival of infected lymphoma cells.
The Journal of experimental medicine Apr, 2004 | Pubmed ID: 15067035
KSHV-positive solid lymphomas represent an extra-cavitary variant of primary effusion lymphoma.
The American journal of surgical pathology Nov, 2004 | Pubmed ID: 15489644
Uncovering the complexities of Kaposi's sarcoma through genome-wide expression analysis.
Genome biology , 2004 | Pubmed ID: 15535873
Distinct subsets of primary effusion lymphoma can be identified based on their cellular gene expression profile and viral association.
Journal of virology Jan, 2005 | Pubmed ID: 15613351
Activation of CD21 and CD23 gene expression by Kaposi's sarcoma-associated herpesvirus RTA.
Journal of virology Apr, 2005 | Pubmed ID: 15795251
Rituximab does not improve clinical outcome in a randomized phase 3 trial of CHOP with or without rituximab in patients with HIV-associated non-Hodgkin lymphoma: AIDS-Malignancies Consortium Trial 010.
Blood Sep, 2005 | Pubmed ID: 15914552
Abbreviated chemotherapy with fludarabine followed by tositumomab and iodine I 131 tositumomab for untreated follicular lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Aug, 2005 | Pubmed ID: 16110029
KSHV G protein-coupled receptor inhibits lytic gene transcription in primary-effusion lymphoma cells via p21-mediated inhibition of Cdk2.
Blood Jan, 2006 | Pubmed ID: 16150942
The KSHV oncoprotein vFLIP contains a TRAF-interacting motif and requires TRAF2 and TRAF3 for signalling.
EMBO reports Jan, 2006 | Pubmed ID: 16311516
NF-kappaB is essential for the progression of KSHV- and EBV-infected lymphomas in vivo.
Blood Apr, 2006 | Pubmed ID: 16380446
Molecular monitoring of chronic myelogenous leukemia: identification of the most suitable internal control gene for real-time quantification of BCR-ABL transcripts.
The Journal of molecular diagnostics : JMD May, 2006 | Pubmed ID: 16645210
Pathogenesis of viral lymphomas.
Cancer treatment and research , 2006 | Pubmed ID: 16704166
beta-Glucuronidase is an optimal normalization control gene for molecular monitoring of chronic myelogenous leukemia.
The Journal of molecular diagnostics : JMD Jul, 2006 | Pubmed ID: 16825513
Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL.
Blood Jan, 2007 | Pubmed ID: 16960154
Kaposi sarcoma-associated herpesvirus in non-Hodgkin lymphoma and reactive lymphadenopathy in Uganda.
Human pathology Feb, 2007 | Pubmed ID: 17097130
KSHV LANA inhibits TGF-beta signaling through epigenetic silencing of the TGF-beta type II receptor.
Blood May, 2008 | Pubmed ID: 18199825
Phase 1/2 trial of BMS-275291 in patients with human immunodeficiency virus-related Kaposi sarcoma: a multicenter trial of the AIDS Malignancy Consortium.
Cancer Mar, 2008 | Pubmed ID: 18224669
EBV LMP2A affects LMP1-mediated NF-kappaB signaling and survival of lymphoma cells by regulating TRAF2 expression.
Blood Apr, 2008 | Pubmed ID: 18230756
Atypical serum immunofixation patterns frequently emerge in immunomodulatory therapy and are associated with a high degree of response in multiple myeloma.
British journal of haematology Dec, 2008 | Pubmed ID: 18950461
HIV-associated lymphomas and gamma-herpesviruses.
Blood Feb, 2009 | Pubmed ID: 18955561
The pathobiology of Kaposi's sarcoma: advances since the onset of the AIDS epidemic.
Journal of cutaneous pathology Nov, 2008 | Pubmed ID: 18976418
Expression of the follicular lymphoma variant translocation 1 gene in diffuse large B-cell lymphoma correlates with subtype and clinical outcome.
American journal of clinical pathology Dec, 2008 | Pubmed ID: 19019774
Role of defective Oct-2 and OCA-B expression in immunoglobulin production and Kaposi's sarcoma-associated herpesvirus lytic reactivation in primary effusion lymphoma.
Journal of virology May, 2009 | Pubmed ID: 19224997
Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma.
Proceedings of the National Academy of Sciences of the United States of America May, 2009 | Pubmed ID: 19429708
Immunophenotypic analysis of AIDS-related diffuse large B-cell lymphoma and clinical implications in patients from AIDS Malignancies Consortium clinical trials 010 and 034.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Oct, 2009 | Pubmed ID: 19752343
Rituximab plus concurrent infusional EPOCH chemotherapy is highly effective in HIV-associated B-cell non-Hodgkin lymphoma.
Blood Apr, 2010 | Pubmed ID: 20023215
Understanding pathogenetic aspects and clinical presentation of primary effusion lymphoma through its derived cell lines.
AIDS (London, England) Feb, 2010 | Pubmed ID: 20051807
NF-kappaB signaling modulation by EBV and KSHV.
Trends in microbiology Jun, 2010 | Pubmed ID: 20452220
Primary effusion lymphoma: genomic profiling revealed amplification of SELPLG and CORO1C encoding for proteins important for cell migration.
The Journal of pathology Oct, 2010 | Pubmed ID: 20690162
NF-κB as a target for oncogenic viruses.
Current topics in microbiology and immunology , 2011 | Pubmed ID: 20845110
Kaposi's sarcoma and its associated herpesvirus.
Nature reviews. Cancer Oct, 2010 | Pubmed ID: 20865011
Phase II AIDS Malignancy Consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma.
Journal of acquired immune deficiency syndromes (1999) Jan, 2011 | Pubmed ID: 21068672
Bortezomib plus CHOP-rituximab for previously untreated diffuse large B-cell lymphoma and mantle cell lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Feb, 2011 | Pubmed ID: 21189393
Kaposi sarcoma herpesvirus (KSHV) vFLIP oncoprotein induces B cell transdifferentiation and tumorigenesis in mice.
The Journal of clinical investigation Mar, 2011 | Pubmed ID: 21339646
A20 (TNFAIP3) genetic alterations in EBV-associated AIDS-related lymphoma.
Blood May, 2011 | Pubmed ID: 21406721
Pilot study of oral valganciclovir therapy in patients with classic Kaposi sarcoma.
The Journal of infectious diseases Apr, 2011 | Pubmed ID: 21450998
Gammaherpesvirus and lymphoproliferative disorders in immunocompromised patients.
Cancer letters Jun, 2011 | Pubmed ID: 21493001
Rapamycin with Antiretroviral Therapy in AIDS-Associated Kaposi Sarcoma: An AIDS Malignancy Consortium Study.
Journal of acquired immune deficiency syndromes (1999) Nov, 2011 | Pubmed ID: 22067664
Kaposi's sarcoma herpesvirus oncogenesis is a notch better in 3D.
Cell host & microbe Dec, 2011 | Pubmed ID: 22177556
Viral lymphomas: can antivirals be used to treat cancer?
Hematology (Amsterdam, Netherlands) Apr, 2012 | Pubmed ID: 22507788
Platelet-associated antibodies, cellular immunity and FCGR3a genotype influence the response to rituximab in immune thrombocytopenia.
British journal of haematology Aug, 2012 | Pubmed ID: 22775462
Targeted genomic sequencing of pediatric Burkitt lymphoma identifies recurrent alterations in antiapoptotic and chromatin-remodeling genes.
Blood Dec, 2012 | Pubmed ID: 23091298
Pegylated liposomal doxorubicin, rituximab, cyclophosphamide, vincristine, and prednisone in AIDS-related lymphoma: AIDS Malignancy Consortium Study 047.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Jan, 2013 | Pubmed ID: 23169503
Multiplexed colorimetric detection of Kaposi's sarcoma associated herpesvirus and Bartonella DNA using gold and silver nanoparticles.
Nanoscale Feb, 2013 | Pubmed ID: 23340972
Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood.
The Journal of experimental medicine Aug, 2013 | Pubmed ID: 23897980
Pathology of lymphoma in HIV.
Current opinion in oncology Sep, 2013 | Pubmed ID: 23942293
Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies.
Blood Oct, 2013 | Pubmed ID: 23943653
The product of Kaposi's sarcoma-associated herpesvirus immediate early gene K4.2 regulates immunoglobulin secretion and calcium homeostasis by interacting with and inhibiting pERP1.
Journal of virology Nov, 2013 | Pubmed ID: 23986581
Gammaherpesviruses and lymphoproliferative disorders.
Annual review of pathology , 2014 | Pubmed ID: 24111911
Solar thermal polymerase chain reaction for smartphone-assisted molecular diagnostics.
Scientific reports Feb, 2014 | Pubmed ID: 24553130
How do viruses trick B cells into becoming lymphomas?
Current opinion in hematology Jul, 2014 | Pubmed ID: 24886824
Detection of Kaposi's sarcoma associated herpesvirus nucleic acids using a smartphone accessory.
Lab on a chip Oct, 2014 | Pubmed ID: 25117534
FOXO1 repression contributes to block of plasma cell differentiation in classical Hodgkin lymphoma.
Blood Nov, 2014 | Pubmed ID: 25232062
KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivo.
Cell cycle (Georgetown, Tex.) , 2014 | Pubmed ID: 25483078
LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis.
The Journal of clinical investigation Jan, 2015 | Pubmed ID: 25485679
Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells.
Blood Feb, 2015 | Pubmed ID: 25488972
Systemic expression of Kaposi sarcoma herpesvirus (KSHV) Vflip in endothelial cells leads to a profound proinflammatory phenotype and myeloid lineage remodeling in vivo.
PLoS pathogens Jan, 2015 | Pubmed ID: 25607954
The tumor virus landscape of AIDS-related lymphomas.
Blood May, 2015 | Pubmed ID: 25827832
AMC 048: modified CODOX-M/IVAC-rituximab is safe and effective for HIV-associated Burkitt lymphoma.
Blood Jul, 2015 | Pubmed ID: 25957391
Kaposi Sarcoma-associated Herpesvirus: mechanisms of oncogenesis.
Current opinion in virology Oct, 2015 | Pubmed ID: 26431609
KS-Detect - Validation of Solar Thermal PCR for the Diagnosis of Kaposi's Sarcoma Using Pseudo-Biopsy Samples.
PloS one , 2016 | Pubmed ID: 26799834
Does persistent HIV replication explain continued lymphoma incidence in the era of effective antiretroviral therapy?
Current opinion in virology Oct, 2016 | Pubmed ID: 27665065
The epichaperome is an integrated chaperome network that facilitates tumour survival.
Nature Oct, 2016 | Pubmed ID: 27706135
Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies.
The Journal of clinical investigation May, 2017 | Pubmed ID: 28504647
Jonathan B. Reichel1,
Jason McCormick2,
Jonathan R. Fromm3,
Olivier Elemento4,
Ethel Cesarman5,
Mikhail Roshal6
1Innovation Laboratory, Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center,
2Flow-Sorting Core Facility, Weill Cornell Medical College,
3Department of Laboratory Medicine, University of Washington,
4Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medical College,
5Department of Pathology and Laboratory Medicine, Weill Cornell Medical College,
6Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center
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