Cheryl Ackert-Bicknell

Circulating levels of IGF-1 directly regulate bone growth and density.

Nitric oxide regulates receptor activator of nuclear factor-kappaB ligand and osteoprotegerin expression in bone marrow stromal cells.

High-resolution genetic map of X-linked juvenile-type granulosa cell tumor susceptibility genes in mouse.

Congenic mice with low serum IGF-I have increased body fat, reduced bone mineral density, and an altered osteoblast differentiation program.

Allelic differences in a quantitative trait locus affecting insulin-like growth factor-I impact skeletal acquisition and body composition.

Genetic variation in femur extrinsic strength in 29 different inbred strains of mice is dependent on variations in femur cross-sectional geometry and bone density.

Chromosomal inversion discovered in C3H/HeJ mice.

Genetic increase in serum insulin-like growth factor-I (IGF-I) in C3H/HeJ compared with C57BL/6J mice is associated with increased transcription from the IGF-I exon 2 promoter.

Femur mechanical properties in the F2 progeny of an NZB/B1NJ x RF/J cross are regulated predominantly by genetic loci that regulate bone geometry.

The Genetics of PPARG and the Skeleton.

Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes.

Mapping genetic loci that regulate lipid levels in a NZB/B1NJxRF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains.

A chromosomal inversion within a quantitative trait locus has a major effect on adipogenesis and osteoblastogenesis.

PPARG by dietary fat interaction influences bone mass in mice and humans.

Strain-specific effects of rosiglitazone on bone mass, body composition, and serum insulin-like growth factor-I.

Marrow fat and the bone microenvironment: developmental, functional, and pathological implications.

A new standard genetic map for the laboratory mouse.

Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map.

Nocturnin: a circadian target of Pparg-induced adipogenesis.

A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR-gamma nuclear translocation.

BMD regulation on mouse distal chromosome 1, candidate genes, and response to ovariectomy or dietary fat.

Functional genomics complements quantitative genetics in identifying disease-gene associations.

Genetic analysis in the Collaborative Cross breeding population.

HDL cholesterol and bone mineral density: is there a genetic link?

Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density.

Canonical A-to-I and C-to-U RNA editing is enriched at 3'UTRs and microRNA target sites in multiple mouse tissues.

Recalculation of 23 mouse HDL QTL datasets improves accuracy and allows for better candidate gene analysis.

Modeling hepatic osteodystrophy in Abcb4 deficient mice.

Impact of the environment on the skeleton: is it modulated by genetic factors?

The need for mouse models in osteoporosis genetics research.

Spontaneous voiding by mice reveals strain-specific lower urinary tract function to be a quantitative genetic trait.

Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.

Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span.

Fixation stability dictates the differentiation pathway of periosteal progenitor cells in fracture repair.

Aging Research Using Mouse Models.

Genetic regulation of bone strength: a review of animal model studies.

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Mapping of Craniofacial Traits in Outbred Mice Identifies Major Developmental Genes Involved in Shape Determination.

Genetic determinants of fibro-osseous lesions in aged inbred mice.

Passenger Gene Mutations: Unwanted Guests in Genetically Modified Mice.

How do bisphosphonates affect fracture healing?

Genetics of aging bone.

Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice.

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.