Ernst Klar

Transformation of the microvascular system during multistage tumorigenesis.

Immunoprophylaxis with basiliximab, a chimeric anti-interleukin-2 receptor monoclonal antibody, in combination with azathioprine-containing triple therapy in liver transplant recipients.

Detection of disseminated medullary thyroid carcinoma cells in cervical lymph nodes by cytokeratin 20 reverse transcription-polymerase chain reaction.

Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication.

Reduction in mortality with delayed surgical therapy of severe pancreatitis.

Ischemic preconditioning by brief extremity ischemia before flap ischemia in a rat model.

Pancreatic capillary blood flow in an improved model of necrotizing pancreatitis in the rat.

Primary colorectal carcinomas and their intrapulmonary metastases: clinical, glyco-, immuno- and lectin histochemical, nuclear and syntactic structure analysis with emphasis on correlation with period of occurrence of metastases and survival.

Detection of hematogenic and lymphogenic tumor cell dissemination in patients with medullary thyroid carcinoma by cytokeratin 20 and preprogastrin-releasing peptide RT-PCR.

Limits of Couinaud's liver segment classification: a quantitative computer-based three-dimensional analysis.

RET proto-oncogene mutations affecting codon 790/791: A mild form of multiple endocrine neoplasia type 2A syndrome?

Different radiogenic effects on microcirculation in healthy pancreas and in pancreatic carcinoma of the rat.

Radiation-induced leukocyte adhesion to endothelium in normal pancreas and in pancreatic carcinoma of the rat.

Assessment of renal graft function by perioperative monitoring of cortical microcirculation in kidney transplantation.

Oxygen radicals promote ICAM-1 expression and microcirculatory disturbances in experimental acute pancreatitis.

Primary human hepatocytes--a valuable tool for investigation of apoptosis and hepatitis B virus infection.

Donor pretreatment with gadolinium chloride improves early graft function and survival after porcine liver transplantation.

Detection and prognostic relevance of cytokeratin 20 in differentiated and anaplastic thyroid carcinomas by RT-PCR.

Effects of heparin in experimental models of acute pancreatitis and post-ERCP pancreatitis.

C1-inhibitor reduces hepatic leukocyte-endothelial interaction and the expression of VCAM-1 in LPS-induced sepsis in the rat.

Expansion of endothelial surface by an increase of vessel diameter during tumor angiogenesis in experimental and hepatocellular and pancreatic cancer.

The effect of adenovirus expressing wild-type p53 on 5-fluorouracil chemosensitivity is related to p53 status in pancreatic cancer cell lines.

Neoadjuvant radiochemotherapy in locally advanced gastric carcinoma.

Control of T-cell-mediated immune response by HLA class I in human pancreatic carcinoma.

Identification of differentially expressed genes after partial rat liver ischemia/reperfusion by suppression subtractive hybridization.

Sustained hypothermia accelerates microvascular thrombus formation in mice.

Axillary-axillary interarterial chest loop conduit as an alternative for chronic hemodialysis access.

HEGPOL: randomized, placebo controlled, multicenter, double-blind clinical trial to investigate hepatoprotective effects of glycine in the postoperative phase of liver transplantation [ISRCTN69350312].

Hepatic platelet and leukocyte adherence during endotoxemia.

Ciclosporin aggravates tissue damage in ischemia reperfusion-induced acute pancreatitis.

Activating anti-CD40 antibodies induce tumour invasion by cytotoxic T-lymphocytes and inhibition of tumour growth in experimental liver cancer.

Postoperative chemotherapy may not be necessary for patients with ypN0-category after neoadjuvant chemoradiotherapy of rectal cancer.

Iliac anastomotic stenting with a biodegradable poly-L-lactide stent: a preliminary study after 1 and 6 weeks.

Penetration of moxifloxacin into the human pancreas following a single intravenous or oral dose.

Effective antitumoral immune responses are not induced by cytosine deaminase suicide gene transfer in a syngeneic rat pancreatic carcinoma model.

Iliac anastomotic stenting with a sirolimus-eluting biodegradable poly-L-lactide stent: a preliminary study after 6 weeks.

Dynamic changes of post-ischemic hepatic microcirculation improved by a pre-treatment of phosphodiesterase-3 inhibitor, milrinone.

Systemic hypothermia increases PAI-1 expression and accelerates microvascular thrombus formation in endotoxemic mice.

Sirolimus-eluting biodegradable poly-L-lactide stent for peripheral vascular application: a preliminary study in porcine carotid arteries.

Darbepoetin-alpha does not promote microvascular thrombus formation in mice: role of eNOS-dependent protection through platelet and endothelial cell deactivation.

Distinct effects of acute and chronic nicotine application on microvascular thrombus formation and endothelial function in male and female mice.

Effect of parathyroidectomy on quality of life and neuropsychological symptoms in primary hyperparathyroidism.

Effect of neoadjuvant chemoradiation on postoperative fecal continence and anal sphincter function in rectal cancer patients.

Induction of an antitumoral immune response by wild-type adeno-associated virus type 2 in an in vivo model of pancreatic carcinoma.

A biodegradable stent based on poly(L-lactide) and poly(4-hydroxybutyrate) for peripheral vascular application: preliminary experience in the pig.

Intensified irinotecan-based neoadjuvant chemoradiotherapy in rectal cancer: four consecutive designed studies to minimize acute toxicity and to optimize efficacy measured by pathologic complete response.

Primary human hepatocytes are protected against complement by multiple regulators.

Quantification of liver perfusion by dynamic magnetic resonance imaging: experimental evaluation and clinical pilot study.

Postoperative care following pancreatic surgery: surveillance and treatment.

Microvascular dysfunction in hepatic ischemia-reperfusion injury in pigs.

Generation of highly pure fusions of colorectal carcinoma and antigen-presenting cells.

Identification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO).

Induction of HSP70 shows differences in protection against I/R injury derived by ischemic preconditioning and intermittent clamping.

Cryopreservation of human colorectal carcinomas prior to xenografting.

Bacteriolytic therapy of experimental pancreatic carcinoma.

Laparoscopic treatment of renal artery entrapment.

Pharmacokinetics and penetration of moxifloxacin into infected diabetic foot tissue in a large diabetic patient cohort.

Extracorporeal cell therapy of septic shock patients with donor granulocytes: a pilot study.

Impact of portal branch ligation on tissue regeneration, microcirculatory response and microarchitecture in portal blood-deprived and undeprived liver tissue.

DTG procurement guidelines in heart beating donors.

Multidrug-resistance proteins are weak tumor associated antigens for colorectal carcinoma.

Multidrug strategies are effective in the treatment of severe experimental pancreatitis.

Immunosuppressants accelerate microvascular thrombus formation in vivo: role of endothelial cell activation.

Bacterial immunotherapy of gastrointestinal tumors.

Combining bacterial-immunotherapy with therapeutic antibodies: a novel therapeutic concept.

Treatment of necrotizing pancreatitis: redefining the role of surgery.

Ex-vivo clonally expanded B lymphocytes infiltrating colorectal carcinoma are of mature immunophenotype and produce functional IgG.

Acute mesenteric ischemia: a vascular emergency.

A novel sialyl Le(X) expression score as a potential prognostic tool in colorectal cancer.

Volume-outcome relationship in pancreatic surgery: the situation in Germany.

R1 resection in pancreatic cancer has significant impact on long-term outcome in standardized pathology modified for routine use.

The "North German Tumor Bank of Colorectal Cancer": status report after the first 2 years of support by the German Cancer Aid Foundation.

Reperfusion of liver graft during transplantation: techniques used in transplant centres within Eurotransplant and meta-analysis of the literature.

Is the lymph node ratio superior to the Union for International Cancer Control (UICC) TNM system in prognosis of colon cancer?

Scoring of human acute pancreatitis: state of the art.

Prognosis of rectal cancer patients improves with downstaging by intensified neoadjuvant radiochemotherapy - a matched pair analysis.

Acute cholecystitis: early versus delayed cholecystectomy, a multicenter randomized trial (ACDC study, NCT00447304).

Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications.

Future perspectives for surgical research in Germany.

Host defense peptides for treatment of colorectal carcinoma - a comparative in vitro and in vivo analysis.

Gastric gastrointestinal stromal tumor lost in the peritoneum after endoscopic resection.

VEGF-releasing suture material for enhancement of vascularization: development, in vitro and in vivo study.

Endoscopic continuity-preserving therapy for esophageal stenosis and perforation following colliquative necrosis.

Establishment and characterization of cell lines from chromosomal instable colorectal cancer.

Reactivity against microsatellite instability-induced frameshift mutations in patients with inflammatory bowel disease.

Graft rinse prior to reperfusion in liver transplantation: literature review and online survey within the Eurotransplant community.

Optimizing the process of nucleofection for professional antigen presenting cells.

Inflammatory Bowel Diseases: Current Medical and Surgical Therapy.

Surgical Principles in the Treatment of Ulcerative Colitis.

Endoscopic Vacuum Therapy in Colorectal Surgery.

Functional Characterization and Drug Response of Freshly Established Patient-Derived Tumor Models with CpG Island Methylator Phenotype.

Surgical Endoscopic Vacuum Therapy for Defects of the Upper Gastrointestinal Tract.

Ectopic Spleen Tissue - an Underestimated Differential Diagnosis of a Hypervascularised Liver Tumour.

Establishment and characterization of HROC69 - a Crohn´s related colonic carcinoma cell line and its matched patient-derived xenograft.

Differential effects of endogenous, phyto and synthetic cannabinoids on thrombogenesis and platelet activity.

The mutational profile and infiltration pattern of murine MLH1-/- tumors: concurrences, disparities and cell line establishment for functional analysis.

Extending the Limits of Resection for Colorectal Liver Metastases.

Open Surgical versus Minimal Invasive Necrosectomy of the Pancreas-A Retrospective Multicenter Analysis of the German Pancreatitis Study Group.

The effects of hydrogen sulfide on platelet-leukocyte aggregation and microvascular thrombolysis.

Tumor Take Rate Optimization for Colorectal Carcinoma Patient-Derived Xenograft Models.

Endoscopic vacuum therapy for various defects of the upper gastrointestinal tract.