George K. Gittes

Defective pulmonary innervation and autonomic imbalance in congenital diaphragmatic hernia.

Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice.

TGFβ receptor signaling is essential for inflammation-induced but not β-cell workload-induced β-cell proliferation.

Hypoglycemia reduces vascular endothelial growth factor A production by pancreatic beta cells as a regulator of beta cell mass.

Neurogenin3 activation is not sufficient to direct duct-to-beta cell transdifferentiation in the adult pancreas.

α-Cells are dispensable in postnatal morphogenesis and maturation of mouse pancreatic islets.

Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis.

Dynamic imaging of pancreatic nuclear factor κB (NF-κB) activation in live mice using adeno-associated virus (AAV) infusion and bioluminescence.

Concise Review: New Insights Into the Role of Macrophages in β-Cell Proliferation.

Defective parasympathetic innervation is associated with airway branching abnormalities in experimental CDH.

The Role of ARF6 in Biliary Atresia.

Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects against Experimental Murine Colitis.

A synopsis of factors regulating beta cell development and beta cell mass.

Epidermal Growth Factor Receptor Signaling Regulates β Cell Proliferation in Adult Mice.

Forkhead Box Protein 1 (FoxO1) Inhibits Accelerated β Cell Aging in Pancreas-specific SMAD7 Mutant Mice.

SMAD3/Stat3 Signaling Mediates β-Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis-Related Diabetes.

GLP-1/Exendin-4 induces β-cell proliferation via the epidermal growth factor receptor.

Gcg knockin mice as a tool for genetic manipulation in pancreatic alpha cells.

Autophagy protects pancreatic beta cell mass and function in the setting of a high-fat and high-glucose diet.

Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes.

Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice.

Evidence of a developmental origin for β-cell heterogeneity using a dual lineage-tracing technology.

Cellular Autophagy in Cells Plays a Role in the Maintenance of Islet Architecture.

SMAD7 enhances adult β-cell proliferation without significantly affecting β-cell function in mice.

Biliary-Atresia-Associated Mannosidase-1-Alpha-2 Gene Regulates Biliary and Ciliary Morphogenesis and Laterality.

TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas.

Developmental biology of the pancreas: a comprehensive review.

Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitis.

Assessing vesicoureteral reflux in live inbred mice via ultrasound with a microbubble contrast agent.

Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium.

No evidence for β cell neogenesis in murine adult pancreas.

Pancreatic duct cells as a source of VEGF in mice.

M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7.

Renal blood flow and oxygenation drive nephron progenitor differentiation.

Pancreatic cell tracing, lineage tagging and targeted genetic manipulations in multiple cell types using pancreatic ductal infusion of adeno-associated viral vectors and/or cell-tagging dyes.

Intraislet Pancreatic Ducts Can Give Rise to Insulin-Positive Cells.

Multiple roles for TGFβ receptor type II in regulating the pancreatic response in acute pancreatitis.

Transient Suppression of TGFβ Receptor Signaling Facilitates Human Islet Transplantation.

PNA lectin for purifying mouse acinar cells from the inflamed pancreas.

Targeted inhibition of pancreatic acinar cell calcineurin is a novel strategy to prevent post-ERCP pancreatitis.

Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion.

Placental growth factor in beta cells plays an essential role in gestational beta-cell growth.

Intra-Amniotic Sildenafil Treatment Promotes Lung Growth and Attenuates Vascular Remodeling in an Experimental Model of Congenital Diaphragmatic Hernia.

Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia.

Chemical pancreatectomy treats chronic pancreatitis while preserving endocrine function in preclinical models.

Insulin-positive ductal cells do not migrate into preexisting islets during pregnancy.

Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma.

Mechanisms of Impaired Lung Development and Ciliation in Mannosidase-1-Alpha-2 () Mutants.

Polarized macrophages promote gestational beta cell growth through extracellular signal-regulated kinase 5 signalling.

Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer.

Bone-marrow derived cells do not contribute to new beta-cells in the inflamed pancreas.

A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.

Intra-amniotic sildenafil administration in rabbits: Safety, pharmacokinetics, organ distribution and histologic evaluation.

Time-dependent effects of endogenous hyperglucagonemia on glucose homeostasis and hepatic glucagon action.

Intra-amniotic sildenafil treatment improves lung blood flow and pulmonary hypertension in congenital diaphragmatic hernia rats.

Intra-Amniotic Sildenafil and Rosiglitazone Late in Gestation Ameliorate the Pulmonary Hypertension Phenotype in Congenital Diaphragmatic Hernia.