Alain Colige

cDNA cloning and expression of bovine procollagen I N-proteinase: a new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components.

Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3.

Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling.

Expression pattern of metalloproteinases and tissue inhibitors of matrix-metalloproteinases in cycling human endometrium.

TIMP-2 and PAI-1 mRNA levels are lower in aneurysmal as compared to athero-occlusive abdominal aortas.

Novel types of mutation responsible for the dermatosparactic type of Ehlers-Danlos syndrome (Type VIIC) and common polymorphisms in the ADAMTS2 gene.

Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility.

MMP-9 regulates both positively and negatively collagen gel contraction: a nonproteolytic function of MMP-9.

Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V.

ADAM metallopeptidase with thrombospondin type 1 motif 2 inactivation reduces the extent and stability of carbon tetrachloride-induced hepatic fibrosis in mice.

Newly identified biologically active and proteolysis-resistant VEGF-A isoform VEGF111 is induced by genotoxic agents.

Matrix metalloproteinase 12 silencing: a therapeutic approach to treat pathological lung tissue remodeling?

Development of a procedure to simultaneously isolate RNA, DNA, and proteins for [corrected] characterizing cells invading or cultured on chitosan scaffolds.

Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity.

Alternative splicing: a promising target for pharmaceutical inhibition of pathological angiogenesis?

MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets.

MicroRNA-21 exhibits antiangiogenic function by targeting RhoB expression in endothelial cells.

RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis.

Development of a chitosan nanofibrillar scaffold for skin repair and regeneration.

Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion.

Metallothionein-dependent up-regulation of TGF-β2 participates in the remodelling of the myxomatous mitral valve.

The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells.

Eccentric training improves tendon biomechanical properties: a rat model.

Effects of platelet-rich plasma (PRP) on the healing of Achilles tendons of rats.

New prospects in the roles of the C-terminal domains of VEGF-A and their cooperation for ligand binding, cellular signaling and vessels formation.

Emerging pathogenic mechanisms in human myxomatous mitral valve: lessons from past and novel data.

Effects of mild cold shock (25°C) followed by warming up at 37°C on the cellular stress response.

18F-FDG uptake assessed by PET/CT in abdominal aortic aneurysms is associated with cellular and molecular alterations prefacing wall deterioration and rupture.

Tgfβ-Smad and MAPK signaling mediate scleraxis and proteoglycan expression in heart valves.

Vascular Endothelial Growth Factor-111 (VEGF-111) and tendon healing: preliminary results in a rat model of tendon injury.

Gene expression study in positron emission tomography-positive abdominal aortic aneurysms identifies CCL18 as a potential biomarker for rupture risk.

Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment.

The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.

Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis.

New biomarkers for primary mitral regurgitation.

ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis.

Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-β signaling as primary targets.

Expanding the clinical and mutational spectrum of the Ehlers-Danlos syndrome, dermatosparaxis type.

Dissection of Iliac Artery in a Patient With Autosomal Dominant Polycystic Kidney Disease: A Case Report.

A Novel Physiological Glycosaminoglycan-Deficient Splice Variant of Neuropilin-1 Is Anti-Tumorigenic In Vitro and In Vivo.

A novel SMAD3 mutation caused multiple aneurysms in a patient without osteoarthritis symptoms.

Circulating microRNAs signature correlates with positive [F]fluorodeoxyglucose-positron emission tomography in patients with abdominal aortic aneurysm.

Chemotherapy induces alternative transcription and splicing: Facts and hopes for cancer treatment.

Skin physiology in microgravity: a 3-month stay aboard ISS induces dermal atrophy and affects cutaneous muscle and hair follicles cycling in mice.

Loss of ADAMTS3 activity causes Hennekam lymphangiectasia-lymphedema syndrome 3.

Innovative methodology for the identification of soluble biomarkers in fresh tissues.