Linyu Shi

High-efficiency somatic reprogramming induced by intact MII oocytes.

Mice generated after round spermatid injection into haploid two-cell blastomeres.

Defects in trophoblast cell lineage account for the impaired in vivo development of cloned embryos generated by somatic nuclear transfer.

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes.

Generation of genetically modified mice by oocyte injection of androgenetic haploid embryonic stem cells.

Secretome profile of mouse oocytes after activation using mass spectrum.

Haploid embryonic stem cells: an ideal tool for mammalian genetic analyses.

Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes.

Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system.

Homology-mediated end joining-based targeted integration using CRISPR/Cas9.

CRISPR/Cas9 - Mediated Precise Targeted Integration In Vivo Using a Double Cut Donor with Short Homology Arms.

One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs.

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.

CRISPR/Cas9-mediated targeted chromosome elimination.

Generation of knock-in cynomolgus monkey via CRISPR/Cas9 editing.

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR-dCas9-activator transgenic mice.