Alexander J. R. Bishop

Homologous Recombination and Its Role in Carcinogenesis.

Role of homologous recombination in carcinogenesis.

Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development.

Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice.

In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer.

Involvement of homologous recombination in carcinogenesis.

An analysis of normalization methods for Drosophila RNAi genomic screens and development of a robust validation scheme.

A network of conserved damage survival pathways revealed by a genomic RNAi screen.

Building and analyzing protein interactome networks by cross-species comparisons.

PARP1 suppresses homologous recombination events in mice in vivo.

Mouse WRN Helicase Domain Is Not Required for Spontaneous Homologous Recombination-Mediated DNA Deletion.

14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasis.

A conditional mouse model for measuring the frequency of homologous recombination events in vivo in the absence of essential genes.

Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-β (TGF-β).

Mice heterozygous for CREB binding protein are hypersensitive to γ-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm.