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Laboratory of Molecular Biology
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CLIP identifies Nova-regulated RNA networks in the brain.
Science (New York, N.Y.) Nov, 2003 | Pubmed ID: 14615540
Nova regulates brain-specific splicing to shape the synapse.
Nature genetics Aug, 2005 | Pubmed ID: 16041372
Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition.
Cell Oct, 2005 | Pubmed ID: 16213216
CLIP: a method for identifying protein-RNA interaction sites in living cells.
Methods (San Diego, Calif.) Dec, 2005 | Pubmed ID: 16314267
RNA binding proteins and the regulation of neuronal synaptic plasticity.
Current opinion in neurobiology Feb, 2006 | Pubmed ID: 16418001
An RNA map predicting Nova-dependent splicing regulation.
Nature Nov, 2006 | Pubmed ID: 17065982
Evolution of Nova-dependent splicing regulation in the brain.
PLoS genetics Oct, 2007 | Pubmed ID: 17937501
Jernej Ule: an RNA runaway success. Interview by Ruth Williams.
The Journal of cell biology Feb, 2008 | Pubmed ID: 18268098
Functional and mechanistic insights from genome-wide studies of splicing regulation in the brain.
Advances in experimental medicine and biology , 2007 | Pubmed ID: 18380345
Ribonucleoprotein complexes in neurologic diseases.
Current opinion in neurobiology Oct, 2008 | Pubmed ID: 18929657
HITS-CLIP yields genome-wide insights into brain alternative RNA processing.
Nature Nov, 2008 | Pubmed ID: 18978773
CLIP: construction of cDNA libraries for high-throughput sequencing from RNAs cross-linked to proteins in vivo.
Methods (San Diego, Calif.) Jul, 2009 | Pubmed ID: 19272451
High-throughput sequencing methods to study neuronal RNA-protein interactions.
Biochemical Society transactions Dec, 2009 | Pubmed ID: 19909262
The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite.
Frontiers in neural circuits , 2010 | Pubmed ID: 20407637
iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution.
Nature structural & molecular biology Jul, 2010 | Pubmed ID: 20601959
iCLIP predicts the dual splicing effects of TIA-RNA interactions.
PLoS biology , 2010 | Pubmed ID: 21048981
TDP-43 regulates its mRNA levels through a negative feedback loop.
The EMBO journal Jan, 2011 | Pubmed ID: 21131904
Understanding splicing regulation through RNA splicing maps.
Trends in genetics : TIG Mar, 2011 | Pubmed ID: 21232811
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.
Nature neuroscience Apr, 2011 | Pubmed ID: 21358640
The RNA-binding protein Rrm4 is essential for efficient secretion of endochitinase Cts1.
Molecular & cellular proteomics : MCP Dec, 2011 | Pubmed ID: 21808052
Analysis of alternative splicing associated with aging and neurodegeneration in the human brain.
Genome research Oct, 2011 | Pubmed ID: 21846794
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes.
Genes & development Oct, 2011 | Pubmed ID: 22012619
Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity.
Nature communications , 2011 | Pubmed ID: 22027593
Protein-RNA interactions: new genomic technologies and perspectives.
Nature reviews. Genetics Feb, 2011 | Pubmed ID: 22251872
Using human pluripotent stem cells to study post-transcriptional mechanisms of neurodegenerative diseases.
Brain research Jan, 2012 | Pubmed ID: 22285437
Medical Research Council - MRC
Julian Konig1,
Kathi Zarnack2,
Gregor Rot3,
Tomaz Curk3,
Melis Kayikci1,
Blaz Zupan3,
Daniel J. Turner4,
Nicholas M. Luscombe2,
Jernej Ule1
1Laboratory of Molecular Biology, Medical Research Council - MRC,
2European Bioinformatics Institute, EMBL Heidelberg,
3Computer and Information Science, University of Ljubljana,
4Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute
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