enhancing-engraftment-human-induced-pluripotent-stem-cell-derived

Enhancing the Engraftment of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes via a Transient Inhibition of Rho Kinase Activity

A crucial factor in improving cellular therapy effectiveness for myocardial regeneration is to safely and efficiently increase the cell engraftment rate. ...

University of Alabama at Birmingham

Here, we generated human cardiac muscle patches (hCMPs) of clinically relevant dimensions (4 cm × 2 cm × 1.25 mm) by suspending cardiomyocytes, smooth muscle cells, and endothelial cells that had been differentiated from human induced-pluripotent stem cells in a fibrin scaffold and then culturing the construct on a dynamic (rocking) platform.

Large Cardiac Muscle Patches Engineered From Human Induced-Pluripotent Stem Cell-Derived Cardiac Cells Improve Recovery From Myocardial Infarction in Swine.

Xi Lou

Department of Biomedical Engineering,
School of Medicine,
School of Engineering,
Department of Biomedical Engineering, School of Medicine, School of Engineering

University of Alabama at Birmingham

Enhancing the Engraftment of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes via a Transient Inhibition of Rho Kinase Activity

Xi Lou

Department of Biomedical Engineering,School of Medicine,School of Engineering,Department of Biomedical Engineering, School of Medicine, School of Engineering

University of Alabama at Birmingham

Enhancing the Engraftment of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes via a Transient Inhibition of Rho Kinase Activity

Department of Biomedical Engineering,
School of Medicine,
School of Engineering,
Department of Biomedical Engineering, School of Medicine, School of Engineering