fabrication-thin-film-silversilver-chloride-electrodes-with-finely

Fabrication of Thin Film Silver/Silver Chloride Electrodes with Finely Controlled Single Layer Silver Chloride

This paper aims to present a protocol to form smooth and well-controlled films of silver/silver chloride (Ag/AgCl) with designated coverage on top of thin ...

The Hong Kong University of Science and Technology

Intra-body communication (IBC) uses the conductive human body as the communication channel for data exchange. As the bio-sensor research is moving towards portable, wearable and implantable designs, IBC has significant potential applications for personal health care. Previous IBC research mainly focused on the electromagnetic (EM) IBC scheme, which resulted in low data rate (kbps). In this paper, we systematically studied the electric field (EF) IBC scheme, which enables 10Mbps data rate. The human body channel is thoroughly measured with attenuation, noise and distortion for the IBC application. High speed EF IBC links are tested with various modulation schemes. The minimum transmission power of different links is measured.

High speed intra-body communication for personal health care.

Skeletal muscle satellite cells (SCs) are adult muscle stem cells responsible for muscle regeneration after acute or chronic injuries. The lineage progression of quiescent SC toward activation, proliferation, and differentiation during the regeneration is orchestrated by cascades of transcription factors (TFs). Here, we elucidate the function of TF Yin Yang1 (YY1) in muscle regeneration. Muscle-specific deletion of YY1 in embryonic muscle progenitors leads to severe deformity of diaphragm muscle formation, thus neonatal death. Inducible deletion of YY1 in SC almost completely blocks the acute damage-induced muscle repair and exacerbates the chronic injury-induced dystrophic phenotype. Examination of SC revealed that YY1 loss results in cell-autonomous defect in activation and proliferation. Mechanistic search revealed that YY1 binds and represses mitochondrial gene expression. Simultaneously, it also stabilizes Hif1α protein and activates Hif1α-mediated glycolytic genes to facilitate a metabolic reprogramming toward glycolysis which is needed for SC proliferation. Altogether, our findings have identified YY1 as a key regulator of SC metabolic reprogramming through its dual roles in modulating both mitochondrial and glycolytic pathways.

Jie Yuan

Department of Electronic and Computer Engineering

The Hong Kong University of Science and Technology

Fabrication of Thin Film Silver/Silver Chloride Electrodes with Finely Controlled Single Layer Silver Chloride

Jie Yuan

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Electronic and Computer Engineering

The Hong Kong University of Science and Technology

Fabrication of Thin Film Silver/Silver Chloride Electrodes with Finely Controlled Single Layer Silver Chloride

Department of Electronic and Computer Engineering