John Metcalfe
Department of Medicine,
Division of Pulmonary and Critical Care Medicine,
Department of Medicine, Division of Pulmonary and Critical Care Medicine
University of California San Francisco
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Clinical characteristics and treatment outcomes of patients with isoniazid-monoresistant tuberculosis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Jan, 2009 | Pubmed ID: 19086909
Evaluation of quantitative IFN-gamma response for risk stratification of active tuberculosis suspects.
American journal of respiratory and critical care medicine Jan, 2010 | Pubmed ID: 19797760
Clinical and radiographic factors do not accurately diagnose smear-negative tuberculosis in HIV-infected inpatients in Uganda: a cross-sectional study.
PloS one Mar, 2010 | Pubmed ID: 20361038
Determinants of multidrug-resistant tuberculosis clusters, California, USA, 2004-2007.
Emerging infectious diseases Sep, 2010 | Pubmed ID: 20735924
Impact of isoniazid resistance-conferring mutations on the clinical presentation of isoniazid monoresistant tuberculosis.
PloS one , 2012 | Pubmed ID: 22649569
Test variability of the QuantiFERON-TB gold in-tube assay in clinical practice.
American journal of respiratory and critical care medicine Jan, 2013 | Pubmed ID: 23103734
Microscopic-observation drug-susceptibility assay for the diagnosis of drug-resistant tuberculosis in harare, zimbabwe.
PloS one , 2013 | Pubmed ID: 23409072
A transcriptional signature for active TB: have we found the needle in the haystack?
PLoS medicine Oct, 2013 | Pubmed ID: 24167454
Rapid molecular testing for TB to guide respiratory isolation in the U.S.: a cost-benefit analysis.
PloS one , 2013 | Pubmed ID: 24278155
Impact of GeneXpert MTB/RIF on patients and tuberculosis programs in a low-burden setting. a hypothetical trial.
American journal of respiratory and critical care medicine Jun, 2014 | Pubmed ID: 24869625
Reproducibility of interferon gamma (IFN-γ) release Assays. A systematic review.
Annals of the American Thoracic Society Oct, 2014 | Pubmed ID: 25188809
Xpert MTB/RIF false detection of rifampin-resistant tuberculosis from prior infection.
American journal of respiratory and critical care medicine Dec, 2014 | Pubmed ID: 25436783
Suboptimal specificity of Xpert MTB/RIF among treatment-experienced patients.
The European respiratory journal May, 2015 | Pubmed ID: 25792637
Quantifying Isoniazid Levels in Small Hair Samples: A Novel Method for Assessing Adherence during the Treatment of Latent and Active Tuberculosis.
PloS one , 2016 | Pubmed ID: 27191185
A multi-analyte panel for non-invasive pharmacokinetic monitoring of second-line anti-tuberculosis drugs.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 07, 2016 | Pubmed ID: 27287660
Tuberculosis progression rates in U.S. Immigrants following screening with interferon-gamma release assays.
BMC public health 08, 2016 | Pubmed ID: 27558397
Defining a Cutoff for Atazanavir in Hair Samples Associated With Virological Failure Among Adolescents Failing Second-Line Antiretroviral Treatment.
Journal of acquired immune deficiency syndromes (1999) 09, 2017 | Pubmed ID: 28520618
Mycobacterium tuberculosis Subculture Results in Loss of Potentially Clinically Relevant Heteroresistance.
Antimicrobial agents and chemotherapy 11, 2017 | Pubmed ID: 28893776
Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: individual patient data meta-analysis.
The Lancet. Global health 02, 2019 | Pubmed ID: 30683238
Point of care Xpert MTB/RIF versus smear microscopy for tuberculosis diagnosis in southern African primary care clinics: a multicentre economic evaluation.
The Lancet. Global health 06, 2019 | Pubmed ID: 31097281
Simultaneous analysis of 11 medications for drug resistant TB in small hair samples to quantify adherence and exposure using a validated LC-MS/MS panel.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 09, 2019 | Pubmed ID: 31369929
More should be done now for patients with TB-associated chronic lung disease.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 10, 2019 | Pubmed ID: 31627778
Correlation of Linezolid Hair Concentrations with Plasma Exposure in Patients with Drug-Resistant Tuberculosis.
Antimicrobial agents and chemotherapy 02, 2020 | Pubmed ID: 31932382
Presentation and outcome of suspected sepsis in a high-HIV burden, high antiretroviral coverage setting.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases Apr, 2020 | Pubmed ID: 32289564
Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples
Andrew Reckers1,
Anita Wen1,
David Aguilar1,
Peter Bacchetti2,
Monica Gandhi3,
John Metcalfe4,
Roy Gerona1
1Department of Obstetrics, Gynecology and Reproductive Sciences, TB Hair Analysis Laboratory, University of California San Francisco,
2Department of Epidemiology and Biostatistics, University of California San Francisco,
3Department of Medicine, Division of HIV, Infectious Diseases, and Global Medicine, University of California San Francisco,
4Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California San Francisco
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