Akihiko Sakashita

Polycomb directs timely activation of germline genes in spermatogenesis.

RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 acetylation for escape gene activation on the sex chromosomes.

Polycomb protein SCML2 facilitates H3K27me3 to establish bivalent domains in the male germline.

Epigenomic and single-cell profiling of human spermatogonial stem cells.

Chromosome Spread Analyses of Meiotic Sex Chromosome Inactivation.

XY oocytes of sex-reversed females with a Sry mutation deviate from the normal developmental process beyond the mitotic stage†.

Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development.

UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells.

Comparative analysis of enteroendocrine cells and their hormones between mouse intestinal organoids and native tissues.

Endogenous retroviruses drive species-specific germline transcriptomes in mammals.

Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition.