Yayoi Obata

Unregulated expression of the imprinted genes H19 and Igf2r in mouse uniparental fetuses.

Nuclear competence for maturation and pronuclear formation in mouse oocytes.

Birth of parthenogenetic mice that can develop to adulthood.

Nuclei of oocytes derived from mouse parthenogenetic embryos are competent to support development to term.

Regulated expression of two sets of paternally imprinted genes is necessary for mouse parthenogenetic development to term.

Oocyte growth-dependent progression of maternal imprinting in mice.

Disruption of parental-specific expression of imprinted genes in uniparental fetuses.

DNA methylation imprints on the IG-DMR of the Dlk1-Gtl2 domain in mouse male germline.

Long-term effects of in vitro growth of mouse oocytes on their maturation and development.

Identification of genes aberrantly expressed in mouse embryonic stem cell-cloned blastocysts.

Protocol for the production of viable bimaternal mouse embryos.

Transmission of Y chromosomes from XY female mice was made possible by the replacement of cytoplasm during oocyte maturation.

Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice.

Epigenetically immature oocytes lead to loss of imprinting during embryogenesis.

Study on the mechanism of maternal imprinting during oocyte growth.

Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks.

The presence of the Y-chromosome, not the absence of the second X-chromosome, alters the mRNA levels stored in the fully grown XY mouse oocyte.

Long exposure to mature ooplasm can alter DNA methylation at imprinted loci in non-growing oocytes but not in prospermatogonia.

Forced expression of DNA methyltransferases during oocyte growth accelerates the establishment of methylation imprints but not functional genomic imprinting.

Establishment of a conditional transgenic system using the 2A peptide in the female mouse germline.

Developmental competence of oocytes grown in vitro: Has it peaked already?

Complete in vitro generation of fertile oocytes from mouse primordial germ cells.

Reconstitution in vitro of the entire cycle of the mouse female germ line.

Differentiation of Mouse Primordial Germ Cells into Functional Oocytes In Vitro.

Reconstitution of mouse oogenesis in a dish from pluripotent stem cells.

Development of fertile mouse oocytes from mitotic germ cells in vitro.

Ectopic expression of DNA methyltransferases DNMT3A2 and DNMT3L leads to aberrant hypermethylation and postnatal lethality in mice.

Dnmt3a2/Dnmt3L Overexpression in the Dopaminergic System of Mice Increases Exercise Behavior through Signaling Changes in the Hypothalamus.

Blocking estrogen-induced AMH expression is crucial for normal follicle formation.

Oocyte-specific gene knockdown by intronic artificial microRNAs driven by Zp3 transcription in mice.