Jack H. Freed

A novel view of domain flexibility in E. coli adenylate kinase based on structural mode-coupling (15)N NMR relaxation.

Protein structure determination using long-distance constraints from double-quantum coherence ESR: study of T4 lysozyme.

Domain flexibility in ligand-free and inhibitor-bound Escherichia coli adenylate kinase based on a mode-coupling analysis of 15N spin relaxation.

Variable-frequency EPR study of Mn(2+)-doped NH(4)Cl(0.9)I(0.1) single crystal at 9.6, 36, and 249.9 GHz: structural phase transition.

End-to-end correlation for a C-12 hydrocarbon chain.

A 2D-ELDOR study of the liquid ordered phase in multilamellar vesicle membranes.

Lipid-gramicidin interactions: dynamic structure of the boundary lipid by 2D-ELDOR.

Ordered and disordered phases coexist in plasma membrane vesicles of RBL-2H3 mast cells. An ESR study.

High resolution electron spin resonance microscopy.

Hydration, structure, and molecular interactions in the headgroup region of dioleoylphosphatidylcholine bilayers: an electron spin resonance study.

Measurement of large distances in biomolecules using double-quantum filtered refocused electron spin-echoes.

Enrichment of endoplasmic reticulum with cholesterol inhibits sarcoplasmic-endoplasmic reticulum calcium ATPase-2b activity in parallel with increased order of membrane lipids: implications for depletion of endoplasmic reticulum calcium stores and apoptosis in cholesterol-loaded macrophages.

Spin-labeled gramicidin a: channel formation and dissociation.

Dynamic molecular structure of DPPC-DLPC-cholesterol ternary lipid system by spin-label electron spin resonance.

The determination of pair distance distributions by pulsed ESR using Tikhonov regularization.

New method for determining tie-lines in coexisting membrane phases using spin-label ESR.

A variable temperature EPR study of Mn(2+)-doped NH(4)Cl(0.9)I(0.1) single crystal at 170 GHz: zero-field splitting parameter and its absolute sign.

Maximum entropy: a complement to Tikhonov regularization for determination of pair distance distributions by pulsed ESR.

Effects of finite pulse width on two-dimensional Fourier transform electron spin resonance.

High-frequency ESR at ACERT.

EPR distance measurements support a model for long-range radical initiation in E. coli ribonucleotide reductase.

Electron spin resonance microscopy applied to the study of controlled drug release.

Coexisting domains in the plasma membranes of live cells characterized by spin-label ESR spectroscopy.

Reconstruction of the chemotaxis receptor-kinase assembly.

Protein dynamics from NMR: the slowly relaxing local structure analysis compared with model-free analysis.

Inter-helix distances in lysophospholipid micelle-bound alpha-synuclein from pulsed ESR measurements.

Methyl dynamics in proteins from NMR slowly relaxing local structure spin relaxation analysis: A new perspective.

Collective fluctuations in ordered fluids investigated by two-dimensional electron-electron double resonance spectroscopy.

Dynamics of the nitroxide side chain in spin-labeled proteins.

Modeling the effects of structure and dynamics of the nitroxide side chain on the ESR spectra of spin-labeled proteins.

Characterizing the structure and dynamics of folded oligomers: Pulsed ESR studies of peptoid helices.

Measuring distances by pulsed dipolar ESR spectroscopy: spin-labeled histidine kinases.

Rigid body refinement of protein complexes with long-range distance restraints from pulsed dipolar ESR.

2D-ELDOR using full S(c-) fitting and absorption lineshapes.

Dynamic molecular structure and phase diagram of DPPC-cholesterol binary mixtures: a 2D-ELDOR study.

Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis.

An improved picture of methyl dynamics in proteins from slowly relaxing local structure analysis of 2H spin relaxation.

Oxygen effects on the EPR signals from wood charcoals: experimental results and the development of a model.

Determination of the oligomeric states of human and rat monoamine oxidases in the outer mitochondrial membrane and octyl beta-D-glucopyranoside micelles using pulsed dipolar electron spin resonance spectroscopy.

Parametrization, molecular dynamics simulation, and calculation of electron spin resonance spectra of a nitroxide spin label on a polyalanine alpha-helix.

Simulating electron spin resonance spectra of nitroxide spin labels from molecular dynamics and stochastic trajectories.

Using Markov models to simulate electron spin resonance spectra from molecular dynamics trajectories.

Membrane-bound alpha-synuclein forms an extended helix: long-distance pulsed ESR measurements using vesicles, bicelles, and rodlike micelles.

Multifrequency electron spin resonance spectra of a spin-labeled protein calculated from molecular dynamics simulations.

A scissors mechanism for stimulation of SNARE-mediated lipid mixing by cholesterol.

Molecular-scale force measurement in a coiled-coil peptide dimer by electron spin resonance.

Fusion peptide from influenza hemagglutinin increases membrane surface order: an electron-spin resonance study.

Determination of tie-line fields for coexisting lipid phases: an ESR study.

Scanned-probe detection of electron spin resonance from a nitroxide spin probe.

Calculation of Double-Quantum-Coherence Two-dimensional Spectra: Distance Measurements and Orientational Correlations.

Structure of the ternary complex formed by a chemotaxis receptor signaling domain, the CheA histidine kinase, and the coupling protein CheW as determined by pulsed dipolar ESR spectroscopy.

Multifrequency electron spin resonance study of the dynamics of spin labeled T4 lysozyme.

A multifrequency EPR study of Fe2+ and Mn2+ ions in a ZnSiF(6).6H2O single crystal at liquid-helium temperatures.

Comment on "The physical basis of model-free analysis of NMR relaxation data from proteins and complex fluids" [J. Chem. Phys. 131, 224507 (2009)].

The lipid-binding domain of wild type and mutant alpha-synuclein: compactness and interconversion between the broken and extended helix forms.

Structural dynamics of bio-macromolecules by NMR: the slowly relaxing local structure approach.

Mechanistic understanding of Pyrococcus horikoshii Dph2, a [4Fe-4S] enzyme required for diphthamide biosynthesis.

Channel and nonchannel forms of spin-labeled gramicidin in membranes and their equilibria.

Backbone dynamics of deoxy and carbonmonoxy hemoglobin by NMR/SRLS.

Methyl dynamics of a Ca2+-calmodulin-peptide complex from NMR/SRLS.

Two conserved residues are important for inducing highly ordered membrane domains by the transmembrane domain of influenza hemagglutinin.

A new Lanczos-based algorithm for simulating high-frequency two-dimensional electron spin resonance spectra.

2D-ELDOR study of heterogeneity and domain structure changes in plasma membrane vesicles upon cross-linking of receptors.

Conformational Distributions and Hydrogen Bonding in Gel and Frozen Lipid Bilayers: A High Frequency Spin-Label ESR Study.