Barbara Leuchs

Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors.

Intranasal vaccination with recombinant adeno-associated virus type 5 against human papillomavirus type 16 L1.

Oncolytic murine autonomous parvovirus, a candidate vector for glioma gene therapy, is innocuous to normal and immunocompetent mouse glial cells.

Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus.

Arming parvoviruses with CpG motifs to improve their oncosuppressive capacity.

Killing of p53-deficient hepatoma cells by parvovirus H-1 and chemotherapeutics requires promyelocytic leukemia protein.

Improvement of gemcitabine-based therapy of pancreatic carcinoma by means of oncolytic parvovirus H-1PV.

Combined prophylactic and therapeutic intranasal vaccination against human papillomavirus type-16 using different adeno-associated virus serotype vectors.

Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells.

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material.

Screening of human tumor antigens for CD4 T cell epitopes by combination of HLA-transgenic mice, recombinant adenovirus and antigen peptide libraries.

Comparison of IL-10 and MCP-1-7ND gene transfer with AAV9 vectors for protection from murine autoimmune myocarditis.

Regression of glioma in rat models by intranasal application of parvovirus h-1.

Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model.

Interferon γ improves the vaccination potential of oncolytic parvovirus H-1PV for the treatment of peritoneal carcinomatosis in pancreatic cancer.

Activation of the human immune system by chemotherapeutic or targeted agents combined with the oncolytic parvovirus H-1.

Retargeting of rat parvovirus H-1PV to cancer cells through genetic engineering of the viral capsid.

Intranasal Vaccination with AAV5 and 9 Vectors Against Human Papillomavirus Type 16 in Rhesus Macaques.