Nicola L. Jones

Helicobacter pylori induces gastric epithelial cell apoptosis in association with increased Fas receptor expression.

Enhanced disease severity in Helicobacter pylori-infected mice deficient in Fas signaling.

Escherichia coli shiga-like toxins induce apoptosis and cleavage of poly(ADP-ribose) polymerase via in vitro activation of caspases.

Detection of Shiga toxin-mediated programmed cell death and delineation of death-signaling pathways.

Helicobacter pylori strains expressing the vacuolating cytotoxin interrupt phagosome maturation in macrophages by recruiting and retaining TACO (coronin 1) protein.

Helicobacter pylori infection interferes with epithelial Stat6-mediated interleukin-4 signal transduction independent of cagA, cagE, or VacA.

Fascination with bacteria-triggered cell death: the significance of Fas-mediated apoptosis during bacterial infection in vivo.

Helicobacter pylori disrupts STAT1-mediated gamma interferon-induced signal transduction in epithelial cells.

Helicobacter pylori induces apoptosis of macrophages in association with alterations in the mitochondrial pathway.

Probiotics reduce bacterial colonization and gastric inflammation in H. pylori-infected mice.

Helicobacter pylori infection and gastric cancer: host, bug, environment, or all three?

Amelioration of the effects of Citrobacter rodentium infection in mice by pretreatment with probiotics.

Canadian Helicobacter Study Group Consensus Conference: Update on the approach to Helicobacter pylori infection in children and adolescents--an evidence-based evaluation.

Pediatric gastrointestinal diseases: are drugs the answer?

Oral vaccination against Helicobacter pylori infection is not effective in mice with Fas ligand deficiency.

Autophagy: healthy eating and self-digestion for gastroenterologists.

Helicobacter pylori cytotoxin-associated gene A activates the signal transducer and activator of transcription 3 pathway in vitro and in vivo.

Effect of Helicobacter pylori's vacuolating cytotoxin on the autophagy pathway in gastric epithelial cells.

Autophagy as an emerging dimension to adaptive and innate immunity.

A review of current guidelines for the management of Helicobacter pylori infection in children and adolescents.

Methods to monitor autophagy in H. pylori vacuolating cytotoxin A (VacA)-treated cells.

Detergent-resistant microdomains mediate activation of host cell signaling in response to attaching-effacing bacteria.

Helicobacter pylori activates calpain via toll-like receptor 2 to disrupt adherens junctions in human gastric epithelial cells.

Helicobacter pylori treatment in the hospital setting: a potential model for developing quality improvement initiatives to prevent missed test results.

Autophagy: a primer for the gastroenterologist/hepatologist.

Helicobacter pylori and immigrant health.

Helicobacter pylori in First Nations and recent immigrant populations in Canada.

Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans.

Crohn disease ATG16L1 polymorphism increases susceptibility to infection with Helicobacter pylori in humans.

Guidelines for the use and interpretation of assays for monitoring autophagy.

Cell culture-based assays to test for bacterial adherence and internalization.

Cell culture assays to evaluate bacterial toxicity and virulence.

Modulation of autophagy by Helicobacter pylori and its role in gastric carcinogenesis.

What is the best regimen for Helicobacter pylori eradication in Canadian Arctic Aboriginals?

Helicobacter pylori inhibits dendritic cell maturation via interleukin-10-mediated activation of the signal transducer and activator of transcription 3 pathway.

Microbial Disruption of Autophagy Alters Expression of the RISC Component AGO2, a Critical Regulator of the miRNA Silencing Pathway.

The Toronto Consensus for the Treatment of Helicobacter pylori Infection in Adults.

Protein kinase C δ signaling is required for dietary prebiotic-induced strengthening of intestinal epithelial barrier function.

VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection.

VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1.

MCOLN1/TRPML1 inhibition - a novel strategy used by to escape autophagic killing and antibiotic eradication therapy .

2019 Harry Shwachman Award: Dr Anne M. Griffiths, MD, FRCPC.

Development of the patient-oriented research curriculum in child health (PORCCH).

Helicobacter pylori Infection.

Vitamin D deficiency enhances expression of autophagy-regulating miR-142-3p in mouse and "involved" IBD patient intestinal tissues.

Under the Radar: Strategies Used by to Evade Host Responses.

High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids.