Nicholas J. Mantis

Selective adherence of IgA to murine Peyer's patch M cells: evidence for a novel IgA receptor.

The viral sigma1 protein and glycoconjugates containing alpha2-3-linked sialic acid are involved in type 1 reovirus adherence to M cell apical surfaces.

Oligosaccharide side chains on human secretory IgA serve as receptors for ricin.

Analysis of adhesion molecules involved in leukocyte homing into the basolateral pockets of mouse Peyer's patch M cells.

Vaccines against the category B toxins: Staphylococcal enterotoxin B, epsilon toxin and ricin.

Ricin induces IL-8 secretion from human monocyte/macrophages by activating the p38 MAP kinase pathway.

Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication.

Characterization of a novel high-affinity monoclonal immunoglobulin G antibody against the ricin B subunit.

Evidence for widespread epithelial damage and coincident production of monocyte chemotactic protein 1 in a murine model of intestinal ricin intoxication.

Inhibition of HIV-1 infectivity and epithelial cell transfer by human monoclonal IgG and IgA antibodies carrying the b12 V region.

Inhibition of Salmonella enterica serovar typhimurium motility and entry into epithelial cells by a protective antilipopolysaccharide monoclonal immunoglobulin A antibody.

Neutralizing monoclonal antibodies directed against defined linear epitopes on domain 4 of anthrax protective antigen.

A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin.

Identification of small-molecule inhibitors of ricin and shiga toxin using a cell-based high-throughput screen.

Recognition of secretory IgA by DC-SIGN: implications for immune surveillance in the intestine.

Secretory IgA: arresting microbial pathogens at epithelial borders.

Identification of new classes of ricin toxin inhibitors by virtual screening.

Folding domains within the ricin toxin A subunit as targets of protective antibodies.

Vaccine-induced intestinal immunity to ricin toxin in the absence of secretory IgA.

Transient suppression of Shigella flexneri type 3 secretion by a protective O-antigen-specific monoclonal IgA.

Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB).

Small-molecule inhibitors of ricin and Shiga toxins.

Role of the mannose receptor (CD206) in innate immunity to ricin toxin.

Immunity to ricin: fundamental insights into toxin-antibody interactions.

Plant-based expression of a partially humanized neutralizing monoclonal IgG directed against an immunodominant epitope on the ricin toxin A subunit.

Association of a protective monoclonal IgA with the O antigen of Salmonella enterica serovar Typhimurium impacts type 3 secretion and outer membrane integrity.

Resolution of two overlapping neutralizing B cell epitopes within a solvent exposed, immunodominant α-helix in ricin toxin's enzymatic subunit.

Sub-domains of ricin's B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodies.

FRUIT, a scar-free system for targeted chromosomal mutagenesis, epitope tagging, and promoter replacement in Escherichia coli and Salmonella enterica.

Identification of small molecules that suppress ricin-induced stress-activated signaling pathways.

Exposure of Salmonella enterica Serovar Typhimurium to a Protective Monoclonal IgA Triggers Exopolysaccharide Production via a Diguanylate Cyclase-Dependent Pathway.

High-Throughput, Cell-Based Screens to Identify Small-Molecule Inhibitors of Ricin Toxin and Related Category B Ribosome Inactivating Proteins (RIPs).