Labs DC0522
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Inositol hexakisphosphate promotes dynamin I- mediated endocytosis.
Proceedings of the National Academy of Sciences of the United States of America May, 2002 | Pubmed ID: 12011438
Nateglinide, but not repaglinide, stimulates growth hormone release in rat pituitary cells by inhibition of K channels and stimulation of cyclic AMP-dependent exocytosis.
European journal of endocrinology / European Federation of Endocrine Societies Jul, 2002 | Pubmed ID: 12088930
Sulfatide controls insulin secretion by modulation of ATP-sensitive K(+)-channel activity and Ca(2+)-dependent exocytosis in rat pancreatic beta-cells.
Diabetes Aug, 2002 | Pubmed ID: 12145165
cPLA2alpha-evoked formation of arachidonic acid and lysophospholipids is required for exocytosis in mouse pancreatic beta-cells.
American journal of physiology. Endocrinology and metabolism Jul, 2003 | Pubmed ID: 12644445
Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.
European journal of pharmacology Apr, 2003 | Pubmed ID: 12679159
Phosphatidylinositol 4-kinase serves as a metabolic sensor and regulates priming of secretory granules in pancreatic beta cells.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2003 | Pubmed ID: 12700357
The imidazoline NNC77-0020 affects glucose-dependent insulin, glucagon and somatostatin secretion in mouse pancreatic islets.
Naunyn-Schmiedeberg's archives of pharmacology Oct, 2003 | Pubmed ID: 13680090
ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells.
Diabetes Dec, 2004 | Pubmed ID: 15561909
Liver X receptor activation stimulates insulin secretion via modulation of glucose and lipid metabolism in pancreatic beta-cells.
Diabetes Dec, 2004 | Pubmed ID: 15561926
Glucose stimulates glucagon release in single rat alpha-cells by mechanisms that mirror the stimulus-secretion coupling in beta-cells.
Endocrinology Nov, 2005 | Pubmed ID: 16081632
Engineering and characterization of the long-acting glucagon-like peptide-1 analogue LY2189265, an Fc fusion protein.
Diabetes/metabolism research and reviews May, 2010 | Pubmed ID: 20503261
Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes.
The Journal of biological chemistry Dec, 2010 | Pubmed ID: 20956533
Small molecule allosteric modulation of the glucagon-like Peptide-1 receptor enhances the insulinotropic effect of oxyntomodulin.
Molecular pharmacology Dec, 2012 | Pubmed ID: 22930710
Regulation of GPR119 receptor activity with endocannabinoid-like lipids.
American journal of physiology. Endocrinology and metabolism Dec, 2012 | Pubmed ID: 23074242
Dorothée Sturm1,2,
Lorella Marselli3,
Florian Ehehalt1,2,
Daniela Richter1,
Marius Distler2,
Stephan Kersting1,2,
Robert Grützmann2,
Krister Bokvist4,
Philippe Froguel5,
Robin Liechti6,
Anne Jörns7,
Paolo Meda8,
Gustavo Bruno Baretton9,
Hans-Detlev Saeger2,
Anke M. Schulte10,
Piero Marchetti3,
Michele Solimena1
1Molecular Diabetology, Paul Langerhans Institute Dresden,
2Department of GI-, Thoracic- and Vascular Surgery, University Hospital Carl Gustav Carus, University of Technology Dresden,
3Department of Endocrinology and Metabolism, Metabolic Unit University of Pisa,
4Labs DC0522, Lilly Corporate Center,
5Genomics, Faculty of Medicine Imperial College London,
6Vital-IT, SIB Swiss Institute of Bioinformatics,
7Clinical Biochemistry, Hannover Medical School,
8Cell Physiology and Metabolism, Medical School, University of Geneva,
9Department of Pathology, University Hospital Carl Gustav Carus, University of Technology Dresden,
10R&D DIAB Division / Translational Medicine, Sanofi-Aventis
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