Walter Rosenthal

The signal peptide of the G protein-coupled human endothelin B receptor is necessary for translocation of the N-terminal tail across the endoplasmic reticulum membrane.

Variant amino acids in the extracellular loops of murine and human vasopressin V2 receptors account for differences in cell surface expression and ligand affinity.

Heteroligomerization of an Aquaporin-2 mutant with wild-type Aquaporin-2 and their misrouting to late endosomes/lysosomes explains dominant nephrogenic diabetes insipidus.

Functional involvement of VAMP/synaptobrevin-2 in cAMP-stimulated aquaporin 2 translocation in renal collecting duct cells.

Cell-biologic and functional analyses of five new Aquaporin-2 missense mutations that cause recessive nephrogenic diabetes insipidus.

The extracellular N terminus of the endothelin B (ETB) receptor is cleaved by a metalloprotease in an agonist-dependent process.

Cyclic AMP is sufficient for triggering the exocytic recruitment of aquaporin-2 in renal epithelial cells.

cAMP-induced AQP2 translocation is associated with RhoA inhibition through RhoA phosphorylation and interaction with RhoGDI.

The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho.

Aquaporin-1, nothing but a water channel.

Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells.

Ligand-dependent differences in the internalization of endothelin A and endothelin B receptor heterodimers.

Pharmacochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors.

Disease-causing V(2) vasopressin receptors are retained in different compartments of the early secretory pathway.

Fluorescence resonance energy transfer analysis reveals the existence of endothelin-A and endothelin-B receptor homodimers.

The signal peptide of the rat corticotropin-releasing factor receptor 1 promotes receptor expression but is not essential for establishing a functional receptor.

Actin remodeling requires ERM function to facilitate AQP2 apical targeting.

Arrestin-independent internalization and recycling of the urotensin receptor contribute to long-lasting urotensin II-mediated vasoconstriction.

The hydrophobic amino acid residues in the membrane-proximal C tail of the G protein-coupled vasopressin V2 receptor are necessary for transport-competent receptor folding.

High-affinity AKAP7delta-protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides.

Spatial organisation of AKAP18 and PDE4 isoforms in renal collecting duct principal cells.

N-terminal proteolysis of the endothelin B receptor abolishes its ability to induce EGF receptor transactivation and contractile protein expression in vascular smooth muscle cells.

Endothelin A and endothelin B receptors differ in their ability to stimulate ERK1/2 activation.

The corticotropin-releasing factor receptor type 2a contains an N-terminal pseudo signal peptide.

Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells.

A Role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle.

Rescue of a nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutant by cell-penetrating peptides.

Microtubules are needed for the perinuclear positioning of aquaporin-2 after its endocytic retrieval in renal principal cells.

AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum.

Derlin-1 and p97/valosin-containing protein mediate the endoplasmic reticulum-associated degradation of human V2 vasopressin receptors.

Compartmentalized cAMP signalling in regulated exocytic processes in non-neuronal cells.

Protein-protein interactions as new drug targets. Preface.

Use of Kaede fusions to visualize recycling of G protein-coupled receptors.

Regulation of aquaporin-2 trafficking.

The sequence after the signal peptide of the G protein-coupled endothelin B receptor is required for efficient translocon gating at the endoplasmic reticulum membrane.

Structural determinants for selective recognition of peptide ligands for endothelin receptor subtypes ETA and ETB.

Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein.

Reciprocal regulation of aquaporin-2 abundance and degradation by protein kinase A and p38-MAP kinase.

Mechanisms of protein kinase A anchoring.

Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes.

Functional significance of cleavable signal peptides of G protein-coupled receptors.

Inhibition of biosynthesis of human endothelin B receptor by the cyclodepsipeptide cotransin.

Small-molecule screening identifies modulators of aquaporin-2 trafficking.