Department of Oncology
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Biodistribution and uptake of 3'-deoxy-3'-fluorothymidine in ENT1-knockout mice and in an ENT1-knockdown tumor model.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine Sep, 2010 | Pubmed ID: 20720035
Synthesis of hypoxia imaging agent 1-(5-deoxy-5-fluoro-α-D-arabinofuranosyl)-2-nitroimidazole using microfluidic technology.
Nuclear medicine and biology Feb, 2011 | Pubmed ID: 21315279
The muscarinic receptor antagonist propiverine exhibits α(1)-adrenoceptor antagonism in human prostate and porcine trigonum.
World journal of urology Apr, 2011 | Pubmed ID: 21336600
Radiopharmacological evaluation of 6-deoxy-6-[18F]fluoro-D-fructose as a radiotracer for PET imaging of GLUT5 in breast cancer.
Nuclear medicine and biology May, 2011 | Pubmed ID: 21531283
Copper-free click chemistry with the short-lived positron emitter fluorine-18.
Organic & biomolecular chemistry Nov, 2011 | Pubmed ID: 21938294
Microfluidic technology: an economical and versatile approach for the synthesis of O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET).
Bioorganic & medicinal chemistry letters Mar, 2012 | Pubmed ID: 22342141
Synthesis and evaluation of fluorobenzoylated di- and tripeptides as inhibitors of cyclooxygenase-2 (COX-2).
Bioorganic & medicinal chemistry Apr, 2012 | Pubmed ID: 22386983
In vitro and in vivo evaluation of [(18)F]F-GAZ, a novel oxygen-mimetic azomycin-glucose conjugate, for imaging hypoxic tumor.
Cancer biotherapy & radiopharmaceuticals Oct, 2012 | Pubmed ID: 22746267
Comparative functional evaluation of immunocompetent mouse breast cancer models established from PyMT-tumors using small animal PET with [(18)F]FDG and [(18)F]FLT.
American journal of nuclear medicine and molecular imaging , 2012 | Pubmed ID: 23133804
Synthesis and evaluation of an 18F-labelled norbornene derivative for copper-free click chemistry reactions.
Organic & biomolecular chemistry Jun, 2013 | Pubmed ID: 23640655
Synthesis, characterisation and evaluation of a novel copper-64 complex with selective uptake in EMT-6 cells under hypoxic conditions.
Dalton transactions (Cambridge, England : 2003) Jul, 2013 | Pubmed ID: 23838751
Synthesis and radiopharmacological evaluation of a high-affinity and metabolically stabilized 18F-labeled bombesin analogue for molecular imaging of gastrin-releasing peptide receptor-expressing prostate cancer.
Nuclear medicine and biology Nov, 2013 | Pubmed ID: 23969085
Synthesis of three 18F-labelled cyclooxygenase-2 (COX-2) inhibitors based on a pyrimidine scaffold.
Organic & biomolecular chemistry Dec, 2013 | Pubmed ID: 24145766
Positron emission tomography radiotracers for imaging hypoxia.
Journal of labelled compounds & radiopharmaceuticals Mar-Apr, 2013 | Pubmed ID: 24285331
Automated synthesis and dosimetry of 6-deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF): a radiotracer for imaging of GLUT5 in breast cancer.
American journal of nuclear medicine and molecular imaging , 2014 | Pubmed ID: 24795839
Synthesis and evaluation of 2-amino-5-(4-[(18)F]fluorophenyl)pent-4-ynoic acid ([(18)F]FPhPA): a novel (18)F-labeled amino acid for oncologic PET imaging.
Nuclear medicine and biology Sep, 2014 | Pubmed ID: 24993371
Rerouting the metabolic pathway of (18)F-labeled peptides: the influence of prosthetic groups.
Bioconjugate chemistry Feb, 2015 | Pubmed ID: 25572982
Erratum: Automated synthesis and dosimetry of 6-deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF): a radiotracer for imaging of GLUT5 in breast cancer.
American journal of nuclear medicine and molecular imaging , 2015 | Pubmed ID: 25625031
Detecting functional changes with [(18)F]FAZA in a renal cell carcinoma mouse model following sunitinib therapy.
EJNMMI research Dec, 2014 | Pubmed ID: 26116107
Immuno-PET of epithelial ovarian cancer: harnessing the potential of CA125 for non-invasive imaging.
EJNMMI research Dec, 2014 | Pubmed ID: 26116121
Radiopharmacological evaluation of (18)F-labeled phosphatidylserine-binding peptides for molecular imaging of apoptosis.
Nuclear medicine and biology Nov, 2015 | Pubmed ID: 26205076
Targeting lysyl oxidase for molecular imaging in breast cancer.
Breast cancer research : BCR Aug, 2015 | Pubmed ID: 26265048
Design, Synthesis, and Evaluation of an (18)F-Labeled Radiotracer Based on Celecoxib-NBD for Positron Emission Tomography (PET) Imaging of Cyclooxygenase-2 (COX-2).
ChemMedChem Oct, 2015 | Pubmed ID: 26287271
Metabolically Stabilized (68)Ga-NOTA-Bombesin for PET Imaging of Prostate Cancer and Influence of Protease Inhibitor Phosphoramidon.
Molecular pharmaceutics Apr, 2016 | Pubmed ID: 26973098
PET imaging of cyclooxygenase-2 (COX-2) in a pre-clinical colorectal cancer model.
EJNMMI research Dec, 2016 | Pubmed ID: 27112768
Automated synthesis of [(18)F]DCFPyL via direct radiofluorination and validation in preclinical prostate cancer models.
EJNMMI research Dec, 2016 | Pubmed ID: 27142881
Synthesis and pre-clinical evaluation of an (18)F-labeled single-chain antibody fragment for PET imaging of epithelial ovarian cancer.
American journal of nuclear medicine and molecular imaging , 2016 | Pubmed ID: 27508105
Targeting Phosphatidylserine with a Cu-Labeled Peptide for Molecular Imaging of Apoptosis.
Molecular pharmaceutics 10, 2016 | Pubmed ID: 27608290
In situ click chemistry generation of cyclooxygenase-2 inhibitors.
Nature communications 02, 2017 | Pubmed ID: 28232747
Proteomic characterization of EL4 lymphoma-derived tumors upon chemotherapy treatment reveals potential roles for lysosomes and caspase-6 during tumor cell death in vivo.
Proteomics Jun, 2017 | Pubmed ID: 28508578
Targeting Prostate-Specific Membrane Antigen (PSMA) with F-18-Labeled Compounds: the Influence of Prosthetic Groups on Tumor Uptake and Clearance Profile.
Molecular imaging and biology 12, 2017 | Pubmed ID: 28639122
Molecular Imaging of GLUT1 and GLUT5 in Breast Cancer: A Multitracer Positron Emission Tomography Imaging Study in Mice.
Molecular pharmacology 02, 2018 | Pubmed ID: 29142019
F-Radiolabeling and In Vivo Analysis of SiFA-Derivatized Polymeric Core-Shell Nanoparticles.
Bioconjugate chemistry 01, 2018 | Pubmed ID: 29202229
Molecular imaging of platelet-derived growth factor receptor-alpha (PDGFRα) in papillary thyroid cancer using immuno-PET.
Nuclear medicine and biology 03, 2018 | Pubmed ID: 29367096
Positron Emission Tomography (PET) and Pharmacokinetics: Classical Blood Sampling Versus Image-Derived Analysis of [18F]FAZA and [18F]FDG in a Murine Tumor Bearing Model.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques , 2018 | Pubmed ID: 29702045
Impact of structural alterations on the radiopharmacological profile of F-labeled pyrimidines as cyclooxygenase-2 (COX-2) imaging agents.
Nuclear medicine and biology Jul - Aug, 2018 | Pubmed ID: 29800798
Expression and function of hexose transporters GLUT1, GLUT2, and GLUT5 in breast cancer-effects of hypoxia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 09, 2018 | Pubmed ID: 29913554
Targeting phosphatidylserine for radionuclide-based molecular imaging of apoptosis.
Apoptosis : an international journal on programmed cell death 04, 2019 | Pubmed ID: 30684144
Inhibition of Autotaxin with GLPG1690 Increases the Efficacy of Radiotherapy and Chemotherapy in a Mouse Model of Breast Cancer.
Molecular cancer therapeutics Jan, 2020 | Pubmed ID: 31548293
Effect of hypoxia on human equilibrative nucleoside transporters hENT1 and hENT2 in breast cancer.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Dec, 2019 | Pubmed ID: 31601121
Repeated Fractions of X-Radiation to the Breast Fat Pads of Mice Augment Activation of the Autotaxin-Lysophosphatidate-Inflammatory Cycle.
Cancers Nov, 2019 | Pubmed ID: 31752313
Radiosynthesis and Biological Evaluation of [F]Triacoxib: A New Radiotracer for PET Imaging of COX-2.
Molecular pharmaceutics Jan, 2020 | Pubmed ID: 31816246
Comparison of scandium-44 g with other PET radionuclides in pre-clinical PET phantom imaging.
EJNMMI physics Dec, 2019 | Pubmed ID: 31832809
Radiometal-Containing Aryl Diazonium Salts for Chemoselective Bioconjugation of Tyrosine Residues.
ACS omega Dec, 2019 | Pubmed ID: 31891090
David Connolly*,1,
Justin J. Bailey*,1,
Harun Ilhan2,3,
Peter Bartenstein2,3,
Carmen Wängler4,
Björn Wängler5,
Melinda Wuest1,
Frank Wuest1,
Ralf Schirrmacher1
1Department of Oncology, University of Alberta,
2Department of Nuclear Medicine, University Hospital of Munich,
3ENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, LMU Munich,
4Biomedical Chemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University,
5Molecular Imaging and Radiochemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University
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