Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal SuturesXiaoyu Tian *1,2,3, Meng Zhang *1,2, Yiming Wu 4, Liying Zhang 1,2, Lingli Zhang 1,2, Xueer Zheng 1,2, Shangkun Ou 1,2, Hao Gu 1,2
1Department of Ophthalmology, the Affiliated Hospital of Guizhou Medical University, 2School of Clinical Medicine, Guizhou Medical University, 3The Second People's Hospital of Guiyang City, 4Department of Biomedical Sciences, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham
We developed a rat model of severe corneal inflammation through corneal epithelium curettage combined with corneal sutures. The study evaluated corneal inflammation patterns, epithelial proliferation, and changes in limbal stem cells under inflammatory conditions.
