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Ohio University Heritage College of Osteopathic Medicine

1 ARTICLES PUBLISHED IN JoVE

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Medicine

Adult and Pediatric Porcine Model of Acute Volume Overload
Bret D. Alvis 1,2, Jenna Helmer Sobey 1, Lexie Vaughn 3, Christina Jelly 1, Dawson Wervey 4, Joyce Cheung-Flynn 3, Marisa Case 1, Colleen Brophy 3, Kyle Hocking 2,3
1Department of Anesthesiology, Vanderbilt University Medical Center, 2Department of Biomedical Engineering, Vanderbilt University, 3Department of Surgery, Vanderbilt University Medical Center, 4Ohio University Heritage College of Osteopathic Medicine

The protocol here shows how continuous administration of crystalloids into the central veins of a euvolemic pig/piglet allows for the appropriate investigation of the physiological effects of acute volume overload.

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