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Daiichi Sankyo Pharma Development

1 ARTICLES PUBLISHED IN JoVE

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Medicine

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Venkatesh Mani 1, Nadia Alie 1, Sarayu Ramachandran 1, Philip M. Robson 1, Cecilia Besa 1, Gregory Piazza 2, Michele Mercuri 3, Michael Grosso 3, Bachir Taouli 1, Samuel Z. Goldhaber 2, Zahi A. Fayad 1
1Department of Radiology, Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, 2Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, 3Daiichi Sankyo Pharma Development

The goal of this study is to use magnetic resonance venography with long-circulating gadolinium-based contrast agent and direct thrombus imaging for quantitative evaluation of DVT volume in a multicenter, clinical trial setting. Inter- and intra-observer variability assessments were conducted, and reproducibility of the protocol was determined.

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