Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in RatsJennifer Altomonte 1, Kim A. Muñoz-Álvarez 2, Katsunori Shinozaki 3, Christine Baumgartner 4, Georgios Kaissis 5, Rickmer Braren 5, Oliver Ebert 1
1II. Medizinische Klinik, Klinikum rechts der Isar der TU München, 2Department of Nuclear Medicine, Klinikum rechts der Isar der TU München, 3Division of Clinical Oncology, Hiroshima Prefectural Hospital, 4Center for Preclinical Research, Klinikum rechts der Isar der TU München, 5Institute for Diagnostic and Interventional Radiology, Klinikum rechts der Isar der TU München
Oncolytic virotherapies are under development as novel therapeutics for the treatment of hepatocellular carcinoma (HCC). Here we describe a method for locoregional therapy of HCC via hepatic arterial administration of oncolytic virus.