A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis ImplantationZhe Liu 1,2, Siling Fu 2,3, Nan Tang 2
1Department of Life Sciences, Peking University, 2National Institute of Biological Sciences, Beijing, 3Graduate School of Peking Union Medical College
Internal lung surface area (ISA) is a critical criterion for assessing lung morphology and physiology in lung diseases and injury-induced alveolar regeneration. We describe here a standardized method that can minimize the measurement bias for ISA in both lung pneumonectomy and prosthesis implantation mouse models.
