Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico MethodsXin Hu 1, Jaimee R. Compton 2, Patricia M. Legler 2
1National Center for Advancing Translational Sciences, National Institutes of Health, 2United States Naval Research Laboratory
We present a general protocol for identifying short stretches of homologous host-pathogen protein sequences (SSHHPS) embedded in the viral polyprotein. SSHHPS are recognized by viral proteases and direct the targeted destruction of specific host proteins by several Group IV viruses.
