Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and RiboswitchesIrina Drachuk 1,2, Svetlana Harbaugh 2, Nancy Kelley-Loughnane 3, Jorge L. Chávez 2
1UES Inc., 2711th Human Performance Wing, Airman Systems Directorate, Air Force Research Laboratory, Wright-Patterson AFB, 3Materials and Manufacturing Directorate, Wright-Patterson AFB
The protocol describes the formation of robust and biocompatible DNA-laden microcapsules as multiplexed in vitro biosensors capable of tracking several ligands.