Pan T. X. Li

Creating hetero-11-mers composed of wild-type and mutant subunits to study RNA binding to TRAP.

Using hetero-11-mers composed of wild type and mutant subunits to study tryptophan binding to TRAP and its role in activating RNA binding.

Characterization of a trp RNA-binding attenuation protein (TRAP) mutant with tryptophan independent RNA binding activity.

Probing the mechanical folding kinetics of TAR RNA by hopping, force-jump, and force-ramp methods.

Determination of thermodynamics and kinetics of RNA reactions by force.

Unusual mechanical stability of a minimal RNA kissing complex.

Force unfolding kinetics of RNA using optical tweezers. I. Effects of experimental variables on measured results.

Real-time control of the energy landscape by force directs the folding of RNA molecules.

How RNA unfolds and refolds.

Mechanical unfolding of two DIS RNA kissing complexes from HIV-1.

The essential role of stacking adenines in a two-base-pair RNA kissing complex.

Analysis of diffuse K+ and Mg2+ ion binding to a two-base-pair kissing complex by single-molecule mechanical unfolding.

Combining temperature and force to study folding of an RNA hairpin.