Jose M. Polo

Aphasia in a farmer following viper bite.

Radiation effects on oxidative metabolism in young and aged rat alveolar macrophages.

Epilepsia partialis continua in progressive multifocal leukoencephalopathy: a motor cortex isolation syndrome.

Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.

Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas.

BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms.

Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR.

CtBP is an essential corepressor for BCL6 autoregulation.

BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells.

Sequential transcription factor targeting for diffuse large B-cell lymphomas.

Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells.

BCL6-mediated attenuation of DNA damage sensing triggers growth arrest and senescence through a p53-dependent pathway in a cell context-dependent manner.

B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma.

A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo.

The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL.

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells.

BCL6 modulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt.

SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells.

A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo.

BCL6 is critical for the development of a diverse primary B cell repertoire.

When fibroblasts MET iPSCs.

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells.

Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.

Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice.

A molecular roadmap of reprogramming somatic cells into iPS cells.

Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency.

Mitochondrial DNA haplotypes define gene expression patterns in pluripotent and differentiating embryonic stem cells.

Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity.

Muscle MRI in severe Guillain-Barré syndrome with motor nerve inexcitability.

Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy.

Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.

Nonanaplastic Pleomorphic Xanthoastrocytoma with Meningeal Dissemination Presenting with Bilateral Visual Loss.

A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.

Reprogramming can be a transforming experience.

Phases of reprogramming.

GM-CSF and MEF-conditioned media support feeder-free reprogramming of mouse granulocytes to iPS cells.