Simon Alford

Gbetagamma acts at the C terminus of SNAP-25 to mediate presynaptic inhibition.

Computational analysis in vitro: dynamics and plasticity of a neuro-robotic system.

Calcium influx-independent depression of transmitter release by 5-HT at lamprey spinal cord synapses.

The requirement of presynaptic metabotropic glutamate receptors for the maintenance of locomotion.

Presynaptic GABAA and GABAB Receptor-mediated Phasic Modulation in Axons of Spinal Motor Interneurons.

Dynamical dimension of a hybrid neurorobotic system.

The pharmacology of vertebrate spinal central pattern generators.

Quantitative investigation of calcium signals for locomotor pattern generation in the lamprey spinal cord.

5-HT prolongs ventral root bursting via presynaptic inhibition of synaptic activity during fictive locomotion in lamprey.

G protein betagamma directly regulates SNARE protein fusion machinery for secretory granule exocytosis.

Location and function of vesicle clusters, active zones and Ca2+ channels in the lamprey presynaptic terminal.

G protein betagamma-subunits activated by serotonin mediate presynaptic inhibition by regulating vesicle fusion properties.

Presynaptic G-protein-coupled receptors regulate synaptic cleft glutamate via transient vesicle fusion.

Gbetagamma interferes with Ca2+-dependent binding of synaptotagmin to the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex.

Brain-machine interactions for assessing the dynamics of neural systems.

Presynaptic G-protein-coupled receptors dynamically modify vesicle fusion, synaptic cleft glutamate concentrations, and motor behavior.

A parallel cholinergic brainstem pathway for enhancing locomotor drive.

New Perspectives on the Dialogue between Brains and Machines.

Phosphorylation-state-dependent regulation of NMDA receptor short-term plasticity modifies hippocampal dendritic Ca2+ transients.

Spotlight on the active zone.

Extracellular pH dynamics of retinal horizontal cells examined using electrochemical and fluorometric methods.

Dual pools of actin at presynaptic terminals.

Role of presynaptic metabotropic glutamate receptors in the induction of long-term synaptic plasticity of vesicular release.

Gβγ inhibits exocytosis via interaction with critical residues on soluble N-ethylmaleimide-sensitive factor attachment protein-25.

Differential regulation of synaptic transmission by pre- and postsynaptic SK channels in the spinal locomotor network.

Synaptic NMDA receptor-dependent Ca²⁺ entry drives membrane potential and Ca²⁺ oscillations in spinal ventral horn neurons.

Forebrain dopamine neurons project down to a brainstem region controlling locomotion.

Fluorescent imaging reports an extracellular alkalinization induced by glutamatergic activation of isolated retinal horizontal cells.

Modulation of neurotransmission by GPCRs is dependent upon the microarchitecture of the primed vesicle complex.

The NHS health check programme in England: a qualitative study.

A synaptic mechanism for network synchrony.

Sensory Activation of Command Cells for Locomotion and Modulatory Mechanisms: Lessons from Lampreys.

A descending dopamine pathway conserved from basal vertebrates to mammals.

Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes.

Gβγ SNARE Interactions and Their Behavioral Effects.

Disabling the Gβγ-SNARE interaction disrupts GPCR-mediated presynaptic inhibition, leading to physiological and behavioral phenotypes.

Extracellular and intracellular sphingosine-1-phosphate distinctly regulates exocytosis in chromaffin cells.

Physiological roles for neuromodulation via G GPCRs working through Gβγ-SNARE interaction.

Quantitation and simulation of single action potential-evoked Ca signals in CA1 pyramidal neuron presynaptic terminals.